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R2 DNA polymorphism
See Factor V R2 DNA MutationRA
See Rheumatoid FactorRA Latex
See Rheumatoid Factor

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Rabies Virus Antibody, Vaccine Response		Test Code: RAV
CPT:	86382
Methodology:	Serum Neutralization Flourecence Antibody.
Testing Schedule:	Routine, 2 times per week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	2 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
A titer of 0.1 IU/mL or greater is considered acceptable per ACIP (Advisory Committee of Immunization Practices (ACIP)
Clinical Utility:
This assay is designed to measure anti-rabies glycoprotein antibodies induced by rabies vaccination only; it should not be used as a tool to assess natural exposure to rabies virus.

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Raji Cell Assay
See Immune Complex C3b Binding Assay

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Random Urine Microalbumin
See Microalbumin, Random Urine

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Rapamune®
See Rapamycin

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Rapamycin		Test Code: SIROL
CPT:	87005
Alternate Name:	Rapamune® Sirolimus
Methodology:	Chemiluminescent Microparticle Enzyme Immunoassay (CMIA)
Testing Schedule:	Routine, 3 times per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	2 mL whole blood
Container:	Lavender top (EDTA) tube
Collection:	Include date and time of last dose on Requisition Form
Special Instructions and/or Comments:
•Store as whole blood in original tube. •DO NOT centrifuge, aliquot or freeze. •Refrigerate only.
Reference Range:
< 20 mg/L
Clinical Utility:
Immunosuppressive therapeutic drug monitoring to assess efficacy and potential toxicity. Peak concentrations are reached in 2 hours following oral administration. Elimination half-life in males is 72 hours; in females 61 hours.

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Rapid, Flu A/B Screen
See Influenza A/B Screen, Rapid

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Rapid Group A Beta-Hemolytic Streptococci Antigen
See Strep A Antigen, Rapid Screen with Reflex to Culture

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Rapid Plasma Reagin		Test Code: RPR
Includes:	•RPR, Qualitative Screen •Reactive screens are titered and reported quantitatively. •Treponemal confirmation by TP-PA methodology will be performed on all reactive screens.
CPT:	86592 Reflexed when appropriate:86593, 86781
Alternate Name:	RPR; Serologic Test for Syphilis; STS; Syphilis Screen; Syphilis Screening Test; Syphilis Serology
Methodology:	Charcoal Flocculation
Testing Schedule:	Routine, daily
Report Available:	1-3 days (may be extended if TP-PA confirmation required)
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
•Not performed on cerebrospinal fluid.For cerebrospinal fluid testing, refer to “VDRL, Cerebrospinal Fluid”. •“Maternal RPR” specimens are obtained post delivery. Reactive results on mother require testing on the newborn. Mother and baby should be performed in parallel for both RPR screen and Treponemal Confirmation. •Cord blood is not accepted for analysis. •The Department of Health requires mandatory reporting of any confirmed positive result.
Reference Range:
•Nonreactive: Suggests no current infection or an effectively treated infection. •Reactive:May indicate past or present infection with T. pallidum.Biological false-positive reactions may occur in acute or chronic infections, autoimmune disease, pregnancy, or drug addiction.Reactive results are best interpreted in parallel with the Treponemal Confirmation assay, TP-PA methodology.
Clinical Utility:
Because RPR is a non-treponemal test, it is useful for screening, monitoring treatment and detecting reinfection.

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RAST
See Allergen Testing, General

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RBC		Test Code: RBC
CPT:	85041
Alternate Name:	Red Blood Cell Count; Erythrocyte Count
Methodology:	Automated Analyzer
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1.5 mL whole blood OR 300-500 µL in BD Microtainer™ tube
Container:	Lavender top (EDTA) tube OR lavender top BD Microtainer™ tube for capillary collection
Reference Range:
Age Red Cell (x 10 12 /L) 0 - 7 days 4.80-6.10 8 - 28 days 4.30-5.50 1 month 3.70-4.90 2 months 3.10-4.30 3 - 5 months 3.80-5.20 6 - 11 months 3.90-5.30 1 - 3 years 3.80-5.20 4 - 5 years 4.00-5.20 6 - 10 years 4.10-5.30 11 - 14 years 4.20-5.40 >15 years (female) 4.20-5.40 >15 years (male) 4.60-6.20
Clinical Utility:
Used in the evaluation of anemia, polycythemia and other hematological disorders.

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RBC Fragility
See Osmotic Fragility, Erythrocyte

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RBC Magnesium
See Magnesium, RBC and Plasma

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RBC Osmotic Fragility
See Osmotic Fragility, Erythrocyte

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Red Cell Fragility
See Osmotic Fragility, Erythrocyte

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Red Blood Cell Cholinesterase
See Cholinesterase, RBC

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Reducing Substances, Semiquantitative, Urine		Test Code: RSUB
CPT:	84999
Alternate Name:	Clinitest® for Sugar; Reducing Substances, Urine; Sugar, Semiquantitative, Urine; Total Reducing Sugars, Urine; Urine Reducing Sugars
Methodology:	Manual
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	2 mL random urine (5 drops, absolute minimum)
Container:	Plastic urine container
Collection:	Freshly voided random urine
Special Instructions and/or Comments:
•Transport to the laboratory immediately. •If delay in transport, refrigerate specimen.
Reference Range:
Negative
Clinical Utility:
Used to detect glycosuria, galactosuria and as an aid to help screen sick newborns and children for various errors of carbohydrate metabolism.

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Reducing Substances, Stool		Test Code: SRSUB
CPT:	84999
Methodology:	Manual
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL fresh liquid stool
Container:	Plastic container
Special Instructions and/or Comments:
•Transport to the laboratory immediately. •If delay in transport, refrigerate specimen.
Reference Range:
Negative
Clinical Utility:
Used in the evaluation of disaccharidase deficiencies.

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Reducing Substances, Urine
See Reducing Substances, Semiquantitative, Urine

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Referral Culture
See Culture, Bacterial, Referred for Identification

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Referred Slides Consultation, Surgical Pathology
See Histopathology, Surgical Pathology Consultation, Outside Slides

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Refractive Index, Urine
See Specific Gravity, Urine

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Refractometer
See Specific Gravity, Body Fluid

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Renal Function Panel		Test Code: RFP
Includes:	•Albumin •Calcium •Carbon Dioxide (CO2) •Chloride •Creatinine •Glucose •Phosphorous •Potassium •Sodium •Urea Nitrogen (BUN) •Anion Gap Calculation •Glomerular Filtration Rate Calculation (GFR)
CPT:	80069
Methodology:	See individual test listings.
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
See individual test listings
Critical Values:
See individual test listings
Clinical Utility:
Used in the evaluation of renal function and renal disorders.

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Renal Pelvic Washing Cytology
See Cytopathology, Fluid

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Renin Activity		Test Code: RENN
CPT:	84244
Alternate Name:	Plasma Renin Activity (PRA)
Methodology:	Radioimmunoassay (RIA)
Testing Schedule:	Routine, 2 times per week
Report Available:	2-4 days
Specimen Requirements:
Minimum Volume:	Volume:2 mL frozen plasma
Container:	2 Pre-chilled Lavender top (EDTA) tubes
Collection:	Patient should be in a seated position (Infants supine).
Special Instructions and/or Comments:
• Place tubes immediately on wet ice after collection. • Transport to the laboratory immediately. • Must be processed and frozen immediately. Centrifuge, transfer into 2 plastic aliquot tubes and freeze. Once frozen, transport specimen submerged in dry ice. NOTE: If multiple specimens are submitted from different sites, all specimens must be accurately labeled WITH THE SITE WRITTEN ON EACH TUBE.
Reference Range:
Accompanies Report Mean data are not standardized as to time of day or diet.
Clinical Utility:
Useful for the investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy. Bartter’s syndrome.

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Resistance to Activated Protein C
See Activated Protein C Resistance

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RESP VIRAL PRF, PCR		Test Code: RVPPR
Includes:	Influenza A/Matrix Gene Influenza A/H1 Influenza A/H3 Influenza B RSV A RSV B Parainfluenza 1 Parainfluenza 2 Parainfluenza 3 Human Metapneumovirus Rhinovirus Adenovirus
CPT:	87798 (X12)
Alternate Name:	Respiratory Viral Profile, PCR
Methodology:	Reverse Transcription Polymerase Chain Platform)
Testing Schedule:	Daily
Report Available:	24-48 hours
Specimen Requirements:
Collection:	• Nasopharyngeal swab (flocked swab) in universal transport media (UTM) • Refrigerated
Special Instructions and/or Comments:
Prior to collection instruct the patient to blow their nose to remove excess mucous. Gently pass the swab through the nose into the posterior nasopharynx. Rub the swab on the nasopharyngeal membrane several times to loosen and collect cellular material. Withdraw the swab and place swab in UTM tube and snap off at the score mark. Securely screw on cap of UTM tube. Label the tube with patient name, date of birth and collection date.
Reference Range:
Not detected.
Clinical Utility:
Simultaneous detection and identification of 12 respiratory virus nucleic acids in nasopharyngeal swabs from patients suspected of respiratory tract infections.

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Respiratory Syncytial Virus Antigen Detection		Test Code: DRSV
CPT:	87420
Alternate Name:	RSV Antigen, Rapid; RSV, Direct Antigen
Methodology:	Enzyme Immunoassay (EIA)
Testing Schedule:	Routine, daily
Report Available:	2 hours
Specimen Requirements:
Minimum Volume:	1 mL nasal aspirate
Container:	Sterile container or nasal aspiration syringe
Collection:	Nasal aspirate
Special Instructions and/or Comments:
Transport specimen refrigerated or on ice within 1 hour of collection.
Reference Range:
Negative
Clinical Utility:
RSV is the most common cause of lower respiratory tract infections in children worldwide. is the leading cause of pneumonia and bronchiolitis in infants. Adults usually have mild respiratory symptoms but elderly patients may experience severe lower respiratory tract disease.

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Respiratory Syncytial Virus Culture
See Culture, Viral, Respiratory
See Reticulocyte Count, Whole Blood

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Retic Count
See Reticulocyte Count, Whole Blood

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Reticulin Antibody
See Reticulin Autoantibody

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Reticulin Autoantibody		Test Code: ARET
CPT:	86256
Alternate Name:	Anti-Reticulin Antibody; Reticulin Antibody
Methodology:	Indirect Fluorescent Antibody (IFA)
Testing Schedule:	Routine, daily
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
<1:40 = Negative; Not detected
Clinical Utility:
Highly specific for untreated celiac disease evaluation.

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Reticulocyte Count, Whole Blood		Test Code: RETC
CPT:	85044, 85045
Alternate Name:	Retic; Retic Count
Methodology:	Automated Analyzer or Manual
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1.5 mL whole blood OR 300-500 µL in BD Microtainer™ tube
Container:	Lavender top (EDTA) tube OR lavender top BD Microtainer™ tube for capillary specimen
Special Instructions and/or Comments:
•Transport to the laboratory immediately. •If delay in transport, specimens stored at room temperature are acceptable for 6-8 hours and refrigerated specimens are acceptable up to 72 hours.
Reference Range:
<8 days 1.8 - 4.6% <2 mths 0.1 - 1.7% <3 mths 0.1 - 2.0% <2 years 0.7 - 2.3% <19 years 0.5 - 1.0% > 19 years 0.8 - 2.5%
Clinical Utility:
Used in the evaluation of anemia and hemorrhage; also as an indicator of erythropoietic activity.

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Retinol, Serum
See Vitamin A

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Reverse T3
See T3, Reverse

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RF
See Rheumatoid Factor

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RF IgM
See Rheumatoid Factor

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Rh (D) Immune Globulin		Test Code: TRHG
Includes:	NOTE: •A Type and Antibody Screen test must be ordered. •A standard dose of Rh (D) Immune Globulin should be administered to Rh (D) negative women within 72 hours following invasive obstetrical procedures (ie, amniocentesis, CVS, PUBS), abdominal trauma, external version, and vaginal bleeding during pregnancy. •Request in the event of transfusion of Rh (D) positive platelets or red cells to an Rh (D) negative female <50 years old.
CPT:	N/A
Alternate Name:	Anti-Rh Globulin; RhoGAM™ Work-up
Methodology:	See individual test listings.
Testing Schedule:	Routine, daily
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	3 mL plasma
Container:	Pink top (EDTA) tube
Special Instructions and/or Comments:
Other obstetrical indications for RhIG include spontaneous or therapeutic abortion, ectopic pregnancy, chronic villus sampling, cordocentesis, antepartum hemorrhage, and fetal death.
Clinical Utility:
Rheumatoid factor is essentially an IgM antibody that is directed toward IgG. Although it is a non-specific marker, it is associated with autoimmunity and rheumatoid arthritis. IgG antibodies may be altered to be recognized as “foreign”, resulting in an autoimmunity.

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Rh (D) Immune Globulin Testing,Antepartum
See Obstetric Profile, Repeat Blood Bank Only

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Rh Type
See ABO and Rh (D) Type

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Rheumatoid Factor		Test Code: RF
CPT:	86431
Alternate Name:	RA; RA Latex; RF; RF IgM
Methodology:	Rate Nephelometry
Testing Schedule:	Routine, 3 times per week
Report Available:	2-4 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
<20 IU/mL
Clinical Utility:
Rheumatoid factor is essentially an IgM antibody that is directed toward IgG. Although it is a non-specific marker, it is associated with autoimmunity and rheumatoid arthritis. IgG antibodies may be altered to be recognized as "foreign", resulting in an autoimmunity.

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RhoGAM™ Work-up
See Rh (D) Immune Globulin

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Ribosomal P Protein Autoantibody		Test Code: RIBPP
CPT:	83516
Methodology:	EIA/LIA
Testing Schedule:	Routine, daily
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
•Refrigerate
Reference Range:
<5.0 Units
Clinical Utility:
Ribosomal P Protein autoantibodies, detected in 45-90% of patients with severe depression or psychosis due to SLE, may also be seen in non-psychotic patients with SLE (7-20%). Autoantibody levels may increase in disease flares and decrease during times of disease remission.

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Rickettsia Antibody Profile		Test Code: RMSF
Includes:	IgG and IgM antibodies to each of the following:Rickettsia rickettsii (Rocky Mountain Spotted Fever) Rickettsia Typhus
CPT:	86757 (X4)
Alternate Name:	Rocky Mountain Spotted Fever/Typhus Fever Antibody Profile; RMSF Antibodies; RMSF IgG/IgM
Methodology:	Indirect Fluorescent Antibody (IFA)
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
•Rocky Mountain Spotted Fever (R. rickettsii antibodies): IgG: <1:64 IgM: <1:64 •Typhus (R. typhi antibodies): •IgG: <1:64 •IgM: <1:64
Clinical Utility:
Helps establish the diagnosis of infection due to Rickettsia in the Rocky Mountain spotted fever group or in the typhus group. Reactivity to R. typhi antigen should be considered ‘group-reactive’ because the R. prowazekii infection also induces antibodies reactive with R. typhi.

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Risperdal®
See Risperidone

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Risperidone		Test Code: RISP
Includes:	Risperidone, OH- Risperidone, Risperidone +OH-Risperidone
CPT:	83789
Alternate Name:	Risperdal®
Methodology:	Liquid Chromatography / Tandem Mass Spectrometry (LC-MS/MS)
Testing Schedule:	1 time per week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	3 mL serum
Container:	Red top tube, no serum separator
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Mean steady-state serum levels of risperidone. OH-Risperidone following daily regimens: 2mg/day:.......................14ng total active drug/mL 6mg/day:.......................45ng total active drug/mL 10mg/day:.....................73ng total active drug/mL 16mg/day:...................110ng total active drug/mL Risperidone and OH-Risperidone are approximately equally effective therefore, the sum of their concentrations are reported as total active drug.
Clinical Utility:
Therapeutic drug monitoring for effective therapy. Risperidone is rapidly converted into its hydroxy metabolite in the liver. Peak concentration of risperidone occurs in about 1 hour following oral administration and for 9-hydroxyrisperidone the peak level is reached at 3 hours (17 hours for poor metabolizers). The elimination half-life of risperidone is 3 hours (20 houre for poor metabolizers), and is 21 hours for hydroxyrisperidone (30 hours for poor metabolizers).

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Ristocetin Cofactor		Test Code: RWF
CPT:	85245
Alternate Name:	vW Factor Assay; vonWillebrand Factor
Methodology:	Aggregometry
Testing Schedule:	Routine, 1 time per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mL plasma split equally into 2 plastic aliquot tubes and FROZEN immediately
Container:	2 Blue top (sodium citrate) tubes
Collection:	See special handling instructions for “Coagulation Studies”, listed under Specimen Collection, Preparation, and Handling Section
Special Instructions and/or Comments:
•Testing is contraindicated for patients on Heparin or Coumadin therapy. •Immediately centrifuge the specimens at 1500-1700 X G for 10 minutes.Avoiding the buffy coat, carefully remove the plasma from the cells using a plastic aliquot pipette.Aliquot the plasma into the required number of plastic aliquot tubes and label with “citrated plasma” labels. •Freeze the aliquoted specimens at –40° to –60°C.Once frozen, transport the specimens submerged in dry ice. Causes for rejection: •Extended transport time to laboratory •Clotted specimens •Hemolyzed specimens •Blue top sodium citrate tubes insufficiently filled •Aliquots not received frozen on dry ice •Frozen aliquots not clearly identified as “citrated plasma”
Reference Range:
50% to 150%
Clinical Utility:
Useful to assist in the diagnosis of von Willebrand syndrome.

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Ristocetin Platelet Aggregation		Test Code: RPAG
Includes:	NOTE :Most commonly performed in conjunction with other von Willebrand disease assays. • Evaluation of platelet aggregation response to ristocetin.
CPT:	85576
Methodology:	Aggregometry
Testing Schedule:	•Testing is performed by appointment only, please schedule in advance.
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	10 mL whole blood at room temperature
Container:	3 Blue top (sodium citrate) tubes
Collection:	instructions for “Coagulation Studies”, listed under Specimen Collection, Preparation, and Handling Section
Special Instructions and/or Comments:
•For 14 days prior to testing, use of drugs that inhibit platelet aggregation are contraindicated (ie, acetylsalicylic acid, antihistamines, chlordiazepoxide, clofibrate, cocaine, corticosteroids, diazepam, dipyridamole, furosemide, gentamicin, ibuprofen, indomethacin, marijuana, phenothiazines, phenylbutazone, propranolol,pyrimidine, sulfinpyrazone, theophylline, tricyclic anti depressants). •Patient should be fasting prior to collecting specimen •Transport tubes at room temperature and deliver immediately to the testing department (testing must be completed within 4 hours of collection).DO NOT chill; platelets are activated at low temperatures. •DO NOT centrifuge or aliquot.Must remain as whole blood in original tube. Causes for rejection •Extended transport time to laboratory •Clotted specimens •Hemolyzed specimens •Blue top sodium citrate tubes insufficiently filled
Reference Range:
81% to 97%
Clinical Utility:
vWD is the most common congenital bleeding disorder. Low levels of Ristocetin cofactor are seen in Type I, Type II and Type III vWD.

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RMSF Antibodies
See Rickettsia Antibody Profile

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RMSF IgG/IgM
See Rickettsia Antibody ProfileRNP, SM
See ENA Autoantibody Profile

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Rocky Mountain Spotted Fever/Typhus Fever Antibody Profile
See Rickettsia Antibody Profile

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Ropes Test, Synovial Fluid
See Mucin Clot TestRotalex®
See Rotavirus Antigen, Stool

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Rotavirus Antigen, Stool		Test Code: ROTV
CPT:	87425
Alternate Name:	Rotalex®; Rotavirus, Direct Detection; Rotazyme®
Methodology:	Enzyme Immunoassay (EIA)
Testing Schedule:	3-5 times per week (daily during peak season)
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	1 mL liquid stool, two rectal swabs, or “pea” size amount of formed stool
Container:	Sterile container or red cap culture swab
Collection:	•Collect specimen as soon as possible after onset of disease (preferably 3-5 days). •To eliminate false-negative results, submit several specimens during the course of illness. NOTE: DO NOT submit in diaper or in O & P transport media.
Special Instructions and/or Comments:
Refrigerate, DO NOT freeze.
Reference Range:
Negative NOTE: A negative result does not exclude the possibility of Rotavirus infection.Small quantities of virus or inadequate/improper sampling may cause false-negative results. Submission of a second specimen may be warranted based on clinical presentation.
Clinical Utility:
Rotavirus is the most important cause of early childhood non-bacterial gastroenteritis with the illness also being observed in the elderly and immunocompromised patients.

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Rotavirus, Direct Detection
See Rotavirus Antigen, Stool

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Rotazyme®
See Rotavirus Antigen, Stool

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Roundworm Identification
See Parasite Identification

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Routine Culture, Bronchial Aspirate
See Culture, Bronchoscopy

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Routine Culture, Cerebrospinal Fluid
See Culture, Cerebrospinal Fluid

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Routine Culture, Sputum
See Culture, Sputum

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Routine Culture, Urine, Clean Catch
See Culture, Urine

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Routine Culture, Wound
See Culture, Wound, Aerobic

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Routine Drug Screen
See Drug Screen Comprehensive, Urine

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Routine Stain, Bacteria
See Gram StainRoutine Urinalysis
See Urinalysis with Reflex Microscopic

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Routine Urine
See Urinalysis with Reflex Microscopic

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RPR
See Rapid Plasma Reagin

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RSV Antigen, Rapid
See Respiratory Syncytial Virus Antigen Detection

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RSV, Direct Antigen (DRSV)
See Culture, Viral, General
See Respiratory Synctial Virus Antigen Detection

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Rubella Antibody Profile		Test Code: RUBP
Includes:	Rubella virus IgG and IgM antibodies
CPT:	86762 (x2)
Alternate Name:	Rubella IgG/IgM
Methodology:	See individual test listings
Testing Schedule:	Routine, 1 time per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
See individual test listings and the following table. Rubella Profile Interpretation IgG IgM Comment N N No detectable antibody to Rubella virus and suggests no current, recent, or past infection.Patient is not immune and is susceptible to primary infection. N P May suggest very early “acute” infection with Rubella virus or recent vaccination. This pattern warrants a second specimen to document seroconversion as well as rule out possible cross-reactive antibodies. P P Suggests current or recent primary infection with Rubella virus. Patients may continue to produce Rubella specific IgM antibody for 1-6 months following a primary infection. On the basis of these results, it is not possible to distinguish the difference between vaccine induced antibody and antibody resulting from natural infection. Results should be interpreted in light of the clinical situation. P N Suggests either past exposure to or vaccination with Rubella virus. Patient is immune.
Clinical Utility:
For the in vitro detection of IgG & IgM antibodies specific for Rubella.

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Rubella IgG Antibody, Immune Status		Test Code: RUBG
Includes:	Rubella IgG antibodies
CPT:	86762
Alternate Name:	German Measles Screen/Titer; Rubella Immune Status; Rubella Screen; Rubella Titer
Methodology:	Microparticle Enzyme Immunoassay (MEIA)
Testing Schedule:	Daily, Mon. - Fri.
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
See table. Rubella IgG Antibody mIU/mL Interpretation Comment <5 Seronegative Indicates no detectable IgG antibody by MEIA and suggests no previous exposure to or vaccination with Rubella virus. Patient is not immune and is therefore susceptible to primary infection. 5-12 Borderline Borderline seropositive for IgG antibody to Rubella virus by MEIA. Antibody level present may not confer immunity >12 Seropositive Indicates detectable IgG antibody and suggests either past exposure to or vaccination with Rubella virus. Patient is immune
Clinical Utility:
Presence of Rubella IgG antibodies indicates current or past infection or vaccination. Acute infections can be serologically confirmed by a significant (2 to 4-fold) rise in Rubella IgG antibody titer in acute and convalescent (collected >7 days after acute specimen) samples, or by the presence of Rubella IgM antibodies.

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Rubella IgG/IgM
See Rubella Antibody Profile

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Rubella IgM
See Rubella IgM Antibody

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Rubella IgM Antibody		Test Code: RUBM
Includes:	Determination of Rubella virus IgM antibody for evaluation of current or recent infection.
CPT:	86762
Alternate Name:	Rubella IgM
Methodology:	Capillary Electrophoresis Immunoassay
Testing Schedule:	Routine, daily
Report Available:	5-7 days
Specimen Requirements:
Container:	1 mL serum
Reference Range:
<0.90 EIA Units
Clinical Utility:
Presence of Rubella IgM antibodies indicates current or recent infection. False positive Rubella IgM results have occurred in patients with parvovirus infection, with positive heterophile test for infectious mononucleosis, or with a positive rheumatoid factor.

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Rubella Immune Status
See Rubella IgG Antibody, Immune Status

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Rubella Screen
See Rubella IgG Antibody, Immune

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Rubeola IgG
See Rubeola IgG Antibody, Immune Status

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Rubeola IgG Antibody, Immune Status		Test Code: ROVA
Includes:	Rubeola IgG antibodies
CPT:	86765
Alternate Name:	Measles Antibody; Measles IgG Antibody; Measles Titer; Rubeola IgG
Methodology:	Enzyme-Linked Immunosorbent Assay (ELISA)
Testing Schedule:	Routine, 2 times per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
Range:See table. Rubeola IgG Antibody Screen ELISA Antibody Index Interpretation Comment <=0.90 Negative Indicates no detectable IgG antibody to Rubeola (Measles) virus. Patient is not immune and therefore susceptible to primary infection. If primary infection is suspected, obtained within days after onset of symptoms may not contain detectable IgG antibodies, and second specimen should be obtained in 14-21 days. 0.91-1.09 Equivocal IgG antibody levels to Rubeola (Measles) virus may not equate with immunity. Suggest a new specimen be submitted for testing. >=1.10 Positive Indicates presence of detectable IgG antibody to Rubeola (Measles) virus. Patient is immune. Results suggest past infection or immunization. Immunity to exogenous reinfection is lifelong, so second attacks of disease are virtually unknown.
Clinical Utility:
The presence of measles specific-IgG antibodies would suggest previous immunization or exposure to the measles virus. In non-immunized individuals, when paired acute and convalescent specimens (two to three weeks apart) are evaluated with a 4-fold or greater rise in measles specific-IgG antibodies, an acute infection is suggested and should be corroborated with clinical presentation.

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Russell’s Viper Venom Time
See Dilute Russell’s Viper Venom Time