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6PD
See Glucose-6-Phosphate Dehydrogenase

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ProfileCardiolipin Antibodies
See Cardiolipin Autoantibody Profile

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Packed Cell Volume
See Hematocrit, Whole Blood

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PACP
See Acid Phosphatase, Prostatic

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Pamelor®
See Nortriptyline

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PANCA
See Neutrophil Cytoplasmic Autoantibody Profile

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Pancreatic Polypeptide		Test Code: PANPP
CPT:	83519
Methodology:	Radioimmunoassay (RIA)
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	3 mL plasma
Container:	2 Lavender top (EDTA) tubes
Collection:	Overnight fast (8 hour minimum) required.
Special Instructions and/or Comments:
•Must be processed and frozen immediately •Centrifuge, transfer to plastic aliquot tube and freeze. Once frozen, transport specimen submerged in dry ice.
Reference Range:
0-19 years:.................Not established 20-29 years:...............< 228 pg/mL 30-39 years:.............. < 249 pg/mL 40-49 years:.............. < 270 pg/mL 50-59 years:.............. < 291 pg/mL 60-69 years:.............. < 312 pg/mL 70-79 years: ............. < 332 pg/mL >80 years:..................Not established
Clinical Utility:
Useful for detection of pancreatic endocrine tumors and assessment of vagal nerve function after meal or sham feeding.

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PAP
See Acid Phosphatase, Prostatic
See Histopathology,Immunoperoxidase Procedures

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Papanicolaou Smear
See Cytolopathology,ThinPrep® Pap Test and ThinPrep® plus Imager

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Pap Smear
See Cytolopathology,ThinPrep® Pap Test and ThinPrep® plus Imager

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Pap Test
See Cytolopathology,ThinPrep® Pap Test and ThinPrep® plus Imager

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Pap Test with HPV Reflex Testing
See Cytolopathology,ThinPrep® Pap Test and ThinPrep® plus Imager

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Paracentesis Fluid Cytology
See Cytopathology, Fluid

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Parainfluenza Virus Antibody Profile		Test Code: PAVA
Includes:	Parainfluenza Virus 1, 2 and 3 antibodies
CPT:	86790 (x3)
Methodology:	Complement Fixation
Testing Schedule:	Routine, Monday-Friday
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
< 1:8...........No antibody detected. > 1:8...........Antibody detected. NOTE Compare acute and convalescent titers for greatest diagnostic value. A four fold or greater increase in titer between acute and convalescent specimens confirms the diagnosis of recent infection.
Clinical Utility:
Single titers of > 1.64 are indicative of recent infection. Titers of 1:8 to 1:32 may be indicative of either past or recent infection, since CF antibody levels persist for only a few months. A four fold increase or greater in titer between acute and convalescent specimens confirms the diagnosis. After initial infection, antibody responses at a later date are often heterotypic and exhibit cross reactivity with other paramyxoviruses (e.g. mumps)

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Parainfluenza Virus Culture
See Culture, Viral, Respiratory

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Parasite Identification		Test Code: PID
Includes:	Examination and identification of parasites or parasite-like specimens extracted from fecal or other specimens.
CPT:	87169
Alternate Name:	•Ascaris; Beef Tapeworm; Diphyllobothrium latum; •Echinococcus; Enterobius; Fish Tapeworm; Gross •Worm Identification; Hydatid Larva; Nematode •Identification; Ova and Parasite, Gross Worm •Identification; Pork Tapeworm; Roundworm •Identification, Taenia sp; Tapeworm Identification See also •Arthropod Identification (Ticks, Fleas, Lice) •Pinworm Identification •Ova and Parasites, Stool
Methodology:	Microscopic Identificiation
Testing Schedule:	Routine, Monday-Friday only
Report Available:	1-3 days
Specimen Requirements:
Container:	Clean, dry container containing parasite
Collection:	Small amount of saline or 10% Formalin may be added to container to cover worm.
Special Instructions and/or Comments:
Maintain specimen at room temperature.
Clinical Utility:
Parasitic diseases around the world have one of the highest morbidity and mortality rates.Proper diagnosis of parasitic infections relies on proper collection, transport and identification of parasites in specimens.

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Parasites, Stool
See Ova and Parasites, Stool

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Parasitology Examination for Malaria
See Blood Parasites

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Parathyroid Hormone, C-Terminal		Test Code: CTPTH
Includes:	NOTE This assay is a substitution for the “Parathyroid Hormone, Mid-Molecule (PTH, Mid-Molecule)” assay which has been discontinued. • Parathyroid Horomone, C terminal • Calcium, total
CPT:	83970, 82310
Alternate Name:	C-Terminal PTH
Methodology:	Radioimmunoassay (RIA); Spectrophotometry
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Centrifuge, transfer to plastic aliquot tube and freeze. Once frozen, transport specimen submerged in dry ice.
Reference Range:
PTH, C-Terminal..................... < 0.9ng/mL Calcium: • < 2 years:.......................7.6 -11mg/dL • < 19 years......................8.4 -10.5 mg/dL • 19 years & older............8.7 -10.4 mg/dL
Clinical Utility:
Useful for clinical assessment of parathyroid gland dysfunction and other disorders of calcium homeostasis. As renal function deteriorates in patients with kidney disease, the clearance of C-Terminal PTH (which is excreted only by the kidney) significantly decreases and its half-life in circulation is prolonged, resulting in strikingly high C-Terminal PTH concentrations even in the absence of parathyroid disase.

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Parathyroid Hormone, Intact, Profile		Test Code: INPHP
Includes:	Calcium Creatinine Intact PTH Phosphorus
CPT:	82310, 82565, 83970, 84100
Alternate Name:	Intact Parathyroid Hormone Profile
Methodology:	See individual test listings
Testing Schedule:	Routine, STAT testing available 0600-2100
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	2 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
•Testing must be performed within 4 hours of collection. •If delay in transport, centrifuge specimen, transfer serum to plastic aliquot tube and refrigerate for up to 48 hours.
Reference Range:
See individual test listings
Critical Values:
See individual test listings
Clinical Utility:
Useful in aiding and assessing the following disorders Primary Hyperparathyroidism, Hypoparathyroidism and Non-Parathyroid Hypercalemia.

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Parathyroid Hormone, Intact, Serum		Test Code: INPH
CPT:	83970
Alternate Name:	Intact Parathyroid Hormone; Intact PTH
Methodology:	Direct Chemilumenescence
Testing Schedule:	Routine, STAT testing available 0600-2100
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
•Testing must be performed within 4 hours of collection. •If delay in transport, centrifuge specimen, transfer serum to plastic aliquot tube and refrigerate for up to 48 hours.
Reference Range:
14.0-72.0 pg/mL
Clinical Utility:
Useful in aiding and assessing the following disorders: Primary Hyperparathyroidism, Hypoparathyroidism and Non-Parathyroid Hypercalemia.

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Parathyroid Hormone Related Peptide		Test Code: PTHRP
CPT:	82397
Alternate Name:	• PTH Related Protein • PTHRP, Parathroid Hormone Related Protein
Methodology:	Immunochemiluminometric Assay (ICMA)
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL plasma
Container:	Prechilled lavender top (EDTA) tube CollectionFasting patient preferred.
Special Instructions and/or Comments:
•Transport to the laboratory immediately. •Centrifuge, transfer to plastic aliquot tube and freeze. Once frozen, transport specimen submerged in dry ice.
Reference Range:
<2.0 pmol/L
Clinical Utility:
Useful for, Diagnosis of HHM ( Humoral hypercalcemia of malignancy) in patients with hypercalcimia and nonelevated PTH. When a patient with HHM has an increased value, the test is useful to monitor treatment

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Parietal Cell Antibody
See Parietal Cell Autoantibody

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Parietal Cell Autoantibody		Test Code: APCA
Includes:	•Parietal Cell Autoantibody •Reflexed when appropriate Quantitative titer on positive screens
CPT:	86255,Reflexed when appropriate 86256
Alternate Name:	Antibody to Gastric Parietal Cells; Anti-Parietal Cell Antibody; APCA; Parietal Cell Antibody
Methodology:	Indirect Fluorescent Antibody (IFA)
Testing Schedule:	Routine, 2 times per week
Report Available:	3-5 days (may be extended if further dilutions required)
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
Negative titer <1:20
Clinical Utility:
Detects autoantibodies useful in the differential diagnosis of pernicious anemia.

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Partial Thromboplastin Time, Activated (APTT), Plasma		Test Code: PTT
CPT:	85730
Alternate Name:	Activated Partial Thromboplastin Time; APTT ; PTT
Methodology:	HNL: Mechanical Clot Detection LPP: Photo Optical Detection
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL citrated plasma
Container:	Full blue top (sodium citrate) tube
Special Instructions and/or Comments:
Non-Heparinized Patients 1. Unopened (capped) tubes, uncentrifuged, or centrifuged stored at 18-24C (room temperature) and tested within 24 hours are accepted. 2. If testing can not be completed within 24 hours, aliquot and freeze plasma according to the special handling instructions for coagulation studies found on page 3.11 of the Handbook. Heparinized Patients 1. Specimen must be centrifuged within 1 hour of collection. 2. If testing can not be completed within 24 hours, aliquot and freeze plasma according to the special handling instructions for coagulation studies found on page 3.11 of the Handbook.
Reference Range:
HNL..........21.6-35.6 seconds* LPP........... 22.9-34.5 seconds* Suggested HNL therapeutic range with anticoagulation with unfractionated heparin. • For venous thrombosis/embolish: 65-95 seconds • For acute coronary syndrome: 55-80 seconds • Concurrent with thrombolytic therapy: 45-65 seconds * Range value varies with reagent lot
Critical Values:
HNL.............>95.0 seconds LPP...............>42.0 seconds* *Range/value varies with reagent lot.
Clinical Utility:
Used in the evaluation of the intrinsic coagulation system, coagulation disorders and deficiencies.Also used in monitoring heparin therapy.

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Partial Thromboplastin Time (APTT) Profile		Test Code: PTTP
Includes:	• PTT • PTT mixing study (immediate and incubated) when appropriate • Thrombin Time (TT) reflexed when appropriate • Reptilase Time (REPTL) reflexed when appropriate
CPT:	85730, Reflexed when appropriate, 85732(X2), 85670, 85635
Alternate Name:	PTT mixing study; PTT Profile
Methodology:	Mechanical Clot Detection
Testing Schedule:	Routine, Monday-Friday only
Report Available:	2-3 days
Specimen Requirements:
Minimum Volume:	5 mL citrated plasma
Container:	4 full Blue top (sodium citrate) tubes
Collection:	See special handling instructions for “Coagulation Studies”, listed under Specimen Collection, Preparation, and Handling Section
Special Instructions and/or Comments:
• Testing is contraindicated for patients on heparin or Coumadin therapy. • Transport to the laboratory immediately. • If testing cannot be performed within 4 hours of collection, platelet pour plasma must be prepared prior to freezing. • Immediately centrifuge specimens at 1700 to 2000 g for 10 minutes • Remove the plasma and dispense into plastic aliquot tube. Spin aliquot for 10 minutes. • Remove the plasma and dispense into another plastic aliquot tube. Spin new aliquot for 10 minutes. Transfer plasma into 8 aliquot tubes and freeze. • Once frozen, specimens should be submerged in dry ice for transport.
Reference Range:
See report
Critical Values:
PTT >95.0 seconds* * Value varies with reagent lot
Clinical Utility:
A PTT mixing study can differentiate between a coagulation factor deficiency or the presence of an inhibitor.

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Parvovirus B19 Antibody Profile		Test Code: PARV
Includes:	IgG and IgM Antibodies
CPT:	86747 (x2)
Methodology:	Enzyme Immunoassay (EIA)
Testing Schedule:	Routine, 1 time per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	Volume1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
•IgG :........................< 0.9 •IgM :.......................< 0.9
Clinical Utility:
Useful for diagnosing recent parvovirus infection (IgM) Assessing past infection (e.g., screening pregnant women) and immunity to parvovirus infection (IgG)

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PAS Stain
See Periodic Acid Schiff Stain

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Pathologic Examination
See Histopathology

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Pathology
See Histopathology

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Pb, Blood
See Lead, Blood

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PCP
See Phencyclidine

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PCV
See Hematocrit, Whole Blood

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Pediatric Allergen Profile
See Allergen Profile, Pediatric

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Pelvic Washing Cytology
See Cytopathology, Fluid

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Pemphigoid
See Skin Autoantibody Profile

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Pemphigus
See Skin Autoantibody Profile

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Pemphigus Antibodies
See Histopathology, Skin Biopsy, Immunofluorescence

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Pentobarbital		Test Code: PENTO
CPT:	82205
Methodology:	Gas Chromatography (GC)
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	2 mL serum
Container:	Red top tube, no serum separator
Reference Range:
•Therapeutic...........1-5 .µg/mL •Treatment of intracranial pressure with supportive therapy Children.......20-30 .µg/mL Adults..........25-35 µg/mL
Clinical Utility:
Useful for monitoring therapy and assessing toxicity. Percent Saturation

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Pericardial Fluid Cytology
See Cytopathology, Fluid

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Pericardiocentesis Fluid Cytology
See Cytopathology, Fluid Periodic Acid Schiff Stain

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PAS		Test Code: PAS
CPT:	88313
Alternate Name:	PAS Stain
Methodology:	Manual
Testing Schedule:	Routine, Monday-Friday only
Report Available:	2-4 days
Specimen Requirements:
Minimum Volume:	2 mL whole blood OR 2 bone marrow films
Container:	Lavender top (EDTA) tube
Collection:	Routine venipuncture OR bone marrow aspiration
Reference Range:
Results interpreted by Hematopathologist.
Clinical Utility:
Used in the evaluation of glycogen, mucopolysaccharides and fungiin tissues.

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Peritoneal Dialysate
See Culture, CAPD Fluid

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Peritoneal Fluid
See Peritoneal Lavage Profile

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Peritoneal Fluid Culture
See Culture, Fluid, Aerobic

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Peritoneal Fluid
See pH, Body Fluid

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Peritoneal Fluid Cytology
See Cytopathology, Fluid

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Peritoneal Washing Cytology
See Cytopathology, Fluid

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Peritoneal Lavage Profile		Test Code: DPL
Includes:	•Amylase, Fluid •Bilirubin, Fluid •Cell Count •Particulate Matter
CPT:	82150, 82247, 89050 , 89051
Alternate Name:	Diagnostic Peritoneal Lavage; Fluid Analysis, Peritoneal Lavage; Peritoneal Fluid
Methodology:	See individual test listings.
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	2 mL fluid in each tube
Container:	Red top tube, no serum separator AND lavender top (EDTA) tube
Special Instructions and/or Comments:
The following values are indicative of a blunt trauma •RBC’s ...............>100,000/cumm •WBC’s ..............>500/cumm •Amylase............ >175 Iu/L
Reference Range:
See Individual test listings

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Peroxidase Anti-Peroxidase
See Histopathology, Immunoperoxidase Procedures

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Peroxisomal Panel
See Fatty Acid Profile, Peroxismal (C22-C26)

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Pertussis Antibody Profile
See Bordetella pertussis Antibody Profile PGH
See Alpha Subunit

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pH, Body Fluid		Test Code: FPH
CPT:	83986
Alternate Name:	Body Fluid pH; Dialysis Fluid pH; Drainage pH; Duodenal Aspirate pH; Gastric Aspirate pH; Peritoneal Fluid pH; Thoracentesis Fluid pH; Urine pH
Methodology:	Potentiometry
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL body fluid
Container:	Red top tube, no serum separator
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Not established, must be interpreted with clinical findings.
Clinical Utility:
Used to determine the pH of body fluid to aid in the evaluation of various conditions.

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pH, Stool		Test Code: STPH
CPT:	83986
Alternate Name:	Stool for pH
Methodology:	Manual
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL fresh liquid stool
Container:	Plastic urine container
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Not established, must be interpreted with clinical findings.
Clinical Utility:
Used to evaluate carbohydrate absorption and lower GI tract disorders.

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pH, Urine		Test Code: PH
CPT:	81002
Alternate Name:	Urine PH
Methodology:	Potentiometry
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	3 mL random urine
Container:	Plastic urine container
Collection:	Freshly voided random urine
Reference Range:
4.5-8.0
Clinical Utility:
Used as a crude measure of the acid/base balance of the body and to evaluate renal function and renal disorders.

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Phencyclidine, Quantitative, Blood		Test Code: BPCP
Includes:	Identification and quantitation of phencyclidine in blood.
CPT:	83992
Methodology:	LC/MS/MS or GC/MS
Testing Schedule:	Once/week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mLs whole blood
Container:	Gray top or lavendar top
Reference Range:
Not established
Clinical Utility:
To determine use of phencyclidine.

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Phencyclidine, Qualitative, Urine		Test Code: PHNC
CPT:	80101
Alternate Name:	Angel Dust; PCP
Methodology:	Immunoassay (IA)
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL urine
Container:	Plastic urine container
Special Instructions and/or Comments:
If for forensic or legal purposes, submit specimen with a completed Drug Testing Request and Chain-of-Custody (HNL-53) Form or Blood Alcohol Toxicology Request/Chain-of-Custody (LAB-53) Form.
Reference Range:
None detected. NOTEConfirmation by GC/MS (gas chromatography/mass spectrometry) available upon request.Contact Customer Care 610-402-8170 for instructions.
Clinical Utility:
A qualitative screen useful for detection of drug abuse/use of phencyclidine.Confirmation of a positive screening result by GC/MS is strongly recommended.

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Phenobarbital		Test Code: PHEN
CPT:	80184
Methodology:	Immunoassay (IA)
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Red top or SST tube
Reference Range:
•Therapeutic.......................15-40 .µg/mL •Toxic ................................>40 .µg/mL
Clinical Utility:
Useful for monitoring therapy and assessing toxicity.

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Phencyclidine, Urine, GCMS		Test Code: GCUP
Includes:	Identification and quantitation of phencyclidine by GCMS
CPT:	83992
Methodology:	Gas Chromatography/Mass Spectroscopy (GC/MS)
Testing Schedule:	3 times/week
Report Available:	2-4 days
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Special Instructions and/or Comments:
If for forensic or legal purposes, submit specimen with a completed Drug Testing Request and Chain-of-Custody (HNL-53) Form or Blood Alcohol Toxicology Request/Chain-of-Custody (LAB-32) Form.
Reference Range:
None present
Clinical Utility:
Useful for the detection and positive identification of phencyclidine in urine.

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Phenytoin		Test Code: DILN
CPT:	80185
Alternate Name:	Dilantin®; Diphenylhydantoin
Methodology:	HNL: Endpoint LPP: Turbidimetric rate
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Red top or SST tube
Collection:	I.V.: 2-4 hours after loading dose. Oral: •Peak = 3-9 hours after dose. •Trough = immediately prior to next dose. NOTE Optimal resampling after change in dosage 48 hours.
Reference Range:
Therapeutic....................10-20 µg/mL
Critical Values:
>30.0 µg/mL
Clinical Utility:
Used to measure the amount of phenytoin in the blood and to determine if the drug concentration is within the therapeutic range.

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Phenytoin, Free		Test Code: FRPH
CPT:	80186
Alternate Name:	Free Dilantin®; Free Phenytoin
Methodology:	Ultrafiltration, Immunoassay (IA)
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum OR plasma
Container:	Red top tube, no serum separator OR green top (lithium heparin) tube
Reference Range:
Therapeutic Free1-2µg/mL
Clinical Utility:
The Phenytoin that circulates in blood is 90 % protein bound under normal circumstances.Since neurologic activity and toxicity of Phenytoin are directly related to the unbound fraction of the drug, measurement of the free or unbound drug may be necessary where altered protein binding is possible, such as in hypoalbuminemia, pregnancy, renal or hepatic failure, the elderly or use of concomitant drug therapy.

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Philadelphia Chromosome
See Chromosome Analysis,Hematological, Bone Marrow

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Phos
See Phosphorus, Serum

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Phosphatase, Alkaline
See Alkaline Phosphatase, Total, Serum

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Phosphatidylcholine Autoantibody Profile		Test Code: PHCHO
Includes:	• Phosphatidylcholine IgG Autoantibodies • Phosphatidylcholine IgM Autoantibodies • Phosphatidylcholine IgA Autoantibodies
CPT:	83520 (X3)
Alternate Name:	Phosphatidylcholine IgG, IgM, & IgA Autoantibodies
Methodology:	EIA
Testing Schedule:	1 time/week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold Top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Phosphatidylcholine IgG Autoantibodies......< 10.0 U/mL Phosphatidylcholine IgM Autoantibodies......< 10.0 U/mL Phosphatidylcholine IgA Autoantibodies.......< 10.0 U/mL
Clinical Utility:
Useful for the detection of antibodies directed at phospholipid epitopes.

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Phosphatidyethanolamine Autoantibody		Test Code: PHETH
Includes:	Phosphatidyethanolamine IgG Autoantibodies, Phosphatidyethanolaminel IgM Autoantibodies, Phosphatidyethanolamine IgA Autoantibodies
CPT:	83520 (X3)
Alternate Name:	Phosphatidyethanolamine IgG, IgM, & IgA Autoantibodies
Methodology:	EIA
Testing Schedule:	1 time/week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	1 mLserum
Container:	Gold Top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Phosphatidyethanolamine IgG Autoantibodies ........< 10.0 U/mL Phosphatidyethanolamine IgM Autoantibodies ........< 10.0 U/mL Phosphatidyethanolamine IgA Autoantibodies ........ < 10.0 U/mL
Clinical Utility:
Useful for the detection of antibodies directed at phospholipid epitopes.

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Phosphatidylinositol Autoantibody Profile		Test Code: PHINO
Includes:	Phosphatidylinositol IgG Autoantibodies, Phosphatidylinositol IgM Autoantibodies, Phosphatidylinositol IgA Autoantibodies
CPT:	83520 (X3)
Alternate Name:	Phosphatidyinositol IgG, IgM, & IgA Autoantibodies
Methodology:	EIA
Testing Schedule:	1 time/week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	1 mLserum
Container:	Gold Top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Phosphatidylinositol IgG Autoantibodies........<10 U/mL Phosphatidylinositole IgM Autoantibodies ..... <10 U/mL Phosphatidylinositole IgA Autoantibodies .......<10 U/mL
Clinical Utility:
Useful for the detection of antibodies directed at phospholipid epitopes.

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Phosphatidylserine Antibodies
See Phosphatidylserine Autoantibody Profile

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Phosphatidylserine Autoantibody Profile		Test Code: PTSAB
Includes:	IgG, IgA and IgM Autoantibodies
CPT:	86148 (x3)
Alternate Name:	Anti-Phosphatidylserine Antibody Profile, G/A/M; Phosphatidylserine G/A/M; Phosphatidylserine Antibodies
Methodology:	Enzyme-Linked Immunosorbent Assay (ELISA)
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	3 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Centrifuge, transfer to plastic aliquot tube and freede Once frozen, transport specimen submerged in dry ice.
Reference Range:
IgG...................<11 GPS U/mL IgM..................<25 MPS U/mL IgA..................<20 APS U/mL IgG <11 GPS U/mL- Antibody not detected >=11 GPS U/mL – Antibody detected IgA <20 APS U/mL – Antibody not detected >=20 APS U/mL – Antibody detected IgM <25 MPS U/mL -Antibody not detected >=25 MPS U/mL – Antibody detected
Clinical Utility:
Phosphatidylserine autoantibodies are associated with SLE, lupus-like diseases and the primary antiphospholipid syndrome. Clinical problems are generally related to arterial and deep venous thromboses, recurrent spontaneous abortion, neurological and cardiological manifestations and thrombocytopenia.

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Phosphatidylserine G/A/M
See Phosphatidylserine Autoantibody Profile

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Phospholipid Antibodies
See Anti-Phospholipid Antibody Profile

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Phospholipid Autoantibodies
See Anti-Phospholipid Antibody Profile

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Phosphorus, Serum		Test Code: PHOS
CPT:	84100
Alternate Name:	Inorganic Phosphate; Phos Inorganic Phosphorus
Methodology:	HNL Endpoint LPP Bichromatic endpoint
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
< 15 days:...........5.0-7.8 mg/dL > 15 days...........4.5-6.5 mg/dL > 2 years.............4.5-5.5 mg/dL > 16 years..........2.5-4.5 mg/dL
Critical Values:
<2.0 mg/dL >7.0 mg/dL
Clinical Utility:
Used in the evaluation of ketoacidosis, malnutrition, conditions that affect the kidneys and gastrointestinal tract, and to evaluate the body’s utilization of calcium.

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Phosphorus, UrineRandom		Test Code: RUPO
CPT:	84105
Alternate Name:	Urine Phos; Urine Phosphorus
Methodology:	Endpoint
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL random urine ContainerPlastic urine container Collection Random
Special Instructions and/or Comments:
and/or CommentsTransport to the laboratory promptly.
Reference Range:
20-86 mg/dL
Clinical Utility:
Use to evaluate phosphorus/calcium balance and phosphorus elimination by the kidneys.

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Phosphorus, Urine24-Hour		Test Code: 24PO
Includes:	Volume Measurement Collection Period Creatinine, Urine Phosphorus, Urine
CPT:	81050, 84105
Alternate Name:	Urine Phos; Urine Phosphorus
Methodology:	Endpoint
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	Entire 24-Hour urine collection
Container:	Entire 24-Hour plastic urine container, no preservative
Collection:	24-Hour urine collection See special instructions for “24-Hour Urine Collection”, listed under Specimen Collection, Preparation, and Handling Section
Special Instructions and/or Comments:
Transport to the laboratory promptly.
Reference Range:
•Creatinine, 24-Hour Urine........... 0.8-2.8 g/24 hours •Phosphorus, 24-Hour Urine.........400-1300 mg/24 hours
Clinical Utility:
Use to evaluate phosphorus/calcium balance and phosphorus elimination by the kidneys.

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Phytanic Acid
See Fatty Acid Profile, Peroxismal (C22-C26)

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Pinworm Identification		Test Code: PINWO
CPT:	87172
Alternate Name:	Enterobius
Methodology:	Microscopic Identification
Testing Schedule:	Routine, Monday–Friday only
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	1 Swube™ OR Scotch® Tape Preparation (clear tape with sticky side down on slide)
Collection:	Touch perianal area with sticky side of Swube™ OR Scotch® tape, early morning prior to bowel movement or bathing, place tape on glass slide, sticky side down.
Reference Range:
No Pinworm observed.
Clinical Utility:
Pinworm infestation is diagnosed by observing eggs that are deposited around the anus.The eggs are not normally seen in fecal specimens.

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Pituitary Gonadotropin
See Follicle Stimulating Hormone, Serum

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PKU Screen
See Newborn Screening, State Mandated

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Placental Tissue Examination
See Histopathology, Placenta

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Plasma Renin Activity
See Renin Activity

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Plasminogen, Activity		Test Code: PLAS
CPT:	85420
Alternate Name:	Functional Plasminogen
Methodology:	Chromogenic Assay
Testing Schedule:	Routine, 1 time per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mL prepared “platelet poor plasma” split equally into 2 plastic aliquot tubes and FROZEN immediately.
Container:	2 Blue top (sodium citrate) tubes
Collection:	See special handling instructions for “Coagulation Studies”, listed under Specimen Collection, Preparation, and Handling Section
Special Instructions and/or Comments:
•Testing is contraindicated for patients on Heparin or Coumadin therapy. •Preparation and submission of “platelet poor plasma” is critical for accurate test performance and interpretation.See collection note above. Causes for rejection •Extended transport time to laboratory •Clotted specimens •Hemolyzed specimens •Blue top sodium citrate tubes insufficiently filled •Aliquots not received frozen on dry ice •Frozen aliquots not clearly identified as “platelet poor plasma”
Reference Range:
67% to 134%
Clinical Utility:
Plasminogen deficiency is associated with detectivefibrinolytic system or hypercoagulable states.

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Plasmodium Smear
See Blood Parasites

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Platelet Aggregatin		Test Code: PAGG
Includes:	Evaluation of Platelet Aggregation response to the following •Adenosine Diphosphate (ADP) •Collagen •Epinephrine •Ristocetin •Reflexed when appropriate •Arachidonic Acid Aggregation
CPT:	85576 (x4) Reflexed when appropriate 85576
Alternate Name:	Aggregometer Test; Platelet Function Studies
Methodology:	Aggregometry
Testing Schedule:	Testing is performed by appointment only, please schedule in advance.
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	30 mL whole blood at room temperature.
Container:	8 Blue top (sodium citrate) tubes
Collection:	See special handling instructions for “Coagulation Studies”, listed under Specimen Collection, Preparation, and Handling Section
Special Instructions and/or Comments:
•For 14 days prior to testing, use of drugs that inhibit platelet aggregation are contraindicated (ie, acetylsalicylic acid, antihistamines, chlordiazepoxide, clofibrate, cocaine, corticosteroids, diazepam, dipyridamole, furosemide, gentamicin, ibuprofen, indomethacin, marijuana, phenothiazines, phenylbutazone, propranolol,pyrimidine, sulfinpyrazone, theophylline, tricyclic anti depressants). •Patient should be fasting prior to collecting specimen •Transport tubes at room temperature and deliver immediately to the testing department (testing must be completed within 4 hours of collection).DO NOT chill; platelets are activated at low temperatures. •DO NOT centrifuge or aliquot.Must remain as whole blood in original tube. Causes for rejection •Extended transport time to laboratory •Clotted specimens •Hemolyzed specimens •Blue top sodium citrate tubes insufficiently filled
Reference Range:
•ADP................................70% to 90% •Epinephrine ...................70% to 90% •Collagen ........................60% to 80% •Ristocetin........................81% to 97% •Arachadonic Acid ..........70% to 90%
Clinical Utility:
Measures adhesion and aggregation of blood platelets.

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Platelet Antibody, Direct		Test Code: DPLA
CPT:	86022
Alternate Name:	Cell Bound Platelet Antibody
Methodology:	Enzyme-Linked Immunosorbent Assay (ELISA)
Testing Schedule:	Routine, daily
Report Available:	10-12 days
Specimen Requirements:
Minimum Volume:	Volume5 mL whole blood
Container:	Yellow top (ACD Solution A) tube
Special Instructions and/or Comments:
•Collect Monday-Friday ONLY before 1400, no holidays.Specimens must arrive in the laboratory no later than 1600. •Store as whole blood in original tube at room temperature. •DO NOT centrifuge, aliquot, refrigerate or freeze. •Patient must have a platelet count above 500 mm3.
Reference Range:
• If positive, add to negative glycoprotein specificity will be identified
Clinical Utility:
Useful for diagnosis of Idiopathic (autoimmune) thrombocytopenia purpura.Diagnosis ofimmunethrombocytopenia associated with SLE or other disorders associated with autoimmune phenomena.

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Platelet Antibody, Indirect		Test Code: APLA
CPT:	86022
Methodology:	Enzyme-Linked Immunosorbent Assa (ELISA)
Testing Schedule:	Routine, 3 times per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	2 mL serum
Container:	Red top tube, no serum separator
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Negative NOTE When the patient’s serum is positive, the specific platelet glycoprotein will be identified as well as the probable specificity. The platelet glycoproteins reported areIIb/IIIa, Ia/IIa, GPIb/IX. In addition, this assayscreens for HLA Class I antibodies, but specificity is notdetermined.
Clinical Utility:
Useful for, Evaluating cases of immune platelet refractoriness, post-transfusion purpura, or neonatal alloimmune thrombocytopenic purpura.

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Platelet Count, Blue Top (Sodium Citrate) Tube		Test Code: PTLVR
Includes:	Evaluation on peripheral smear
CPT:	85049
Methodology:	Automated Analyzer
Testing Schedule:	Routine STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1.5 mL whole blood
Container:	Full blue top (sodium citrate) tube
Special Instructions and/or Comments:
DO NOT spin.
Reference Range:
< 4days:......................100-350x109 >4 days.......................100-400x109/L >1 month:...................150-400x109/L
Critical Values:
<50 x 109/L >750 x 109/L
Clinical Utility:
Used to determine the platelet count when clumped platelets were present with the lavender top(EDTA) tube.

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Platelet Count, Whole Blood		Test Code: PTL
Includes:	Automated Platelet Count Evaluation of peripheral smear if deemed necessary by set laboratory criteria
CPT:	85049
Alternate Name:	Thrombocyte Count
Methodology:	Automated Analyzer
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1.5 mL whole blood OR 300- 500 µL in BD Microtainer™ tube
Container:	Lavender top (EDTA) tube OR lavender top BD Microtainer™ tube for capillary collection.
Special Instructions and/or Comments:
If clumped platelets are detected and an exact Platelet Count is desired, it is recommended that a follow up specimen be submitted for a Platelet Count, Blue Top (Sodium Citrate) Tube (PTLVR).
Reference Range:
<4 days ................................100-350x109/L >=4 days...............................100-400x109/L >=1 month ...........................150-400x109/L
Critical Values:
<50 x 109/L >750 x 109/L
Clinical Utility:
Used to evaluate and monitor bleeding and other hematological and coagulation disorders, DIC, leukemias and chemotherapeutic management of malignant disease.

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Platelet Function Studies
See Platelet Aggregation

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Pleural Fluid Culture
See Culture, Fluid, Aerobic

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Pleural Fluid Cytology
See Cytopathology, Fluid

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Pleural Fluid Profile		Test Code: PFA
Includes:	Cell Count Glucose, Fluid Lactate Dehydrogenase, Fluid Protein, Total, Fluid
CPT:	89050, 89051, 82945, 83615, 84157, 88107
Alternate Name:	Fluid Analysis, Pleural Fluid
Methodology:	See individual test listings.
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	2 mL body fluid in each tube
Container:	Red top tube, no serum separator AND lavender top (EDTA) tube
Reference Range:
See individual test listings.
Clinical Utility:
Used to evaluate the cause of pleural effusions.

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PM-1 Antibody
See PM/Scl Autoantibody

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PM/Scl AutoantibodyA		Test Code: PM1B
CPT:	86331
Alternate Name:	Anti-PM-1 Antibody; PM-1 Antibody; Polymositis- Scleroderma Antibody
Methodology:	Immunodiffusion
Testing Schedule:	Routine, 1 time per week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate

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Pneumococcal Antibody Profile, Vaccine Response		Test Code: PNMPR
Includes:	IgG Antibodies to the following Streptocococcus pneumoniae serotypes 1, 2, 3, 4 , 5, 8, 9N, 12F, 14, 17F, 19F, 20, 22F, 23F, 6B, 10A, 11A, 7F, 15B, 18C, 19A, 9V, and 33F.
CPT:	86317 (x23)
Methodology:	Microsphere Photometry
Testing Schedule:	Routine, Monday-Friday ONLY
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
•Centrifuge, transfer to plastic aliquot tube and freeze.Once frozen, transport specimen submerged in dry ice. •Please note if specimens are pre- or post-vaccination.
Reference Range:
See report
Clinical Utility:
Useful for • Assessing the response to active immunization with nonconjugated 23-valent vaccines. • Determining the ability of an individual to respond to polysacchride antigen.

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Pneumococcal IgG Antibody 23 Serotypes
See Pneumococcal Antibody Profile, Vaccine Response

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Pneumocystis carinii, Direct Fluorescence		Test Code: DFPC
CPT:	87281
Alternate Name:	Pneumocystis carinii Stain
Methodology:	Direct Immunofluorescence
Report Available:	1 day
Special Instructions and/or Comments:
Transport to the laboratory within 1 hour of collection or refrigerate for up to 24 hours.
Reference Range:
No Pneumocystis seen
Clinical Utility:
Pneumocystis carinii can infect the lungs and cause a lethal pneumonia in immunocompromised patients and is the leading opportunistic infection associated with AIDS.

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Pneumocystis carinii Stain
See Pneumocystis carinii, Direct Fluorescence
See Histopathology, Pneumocystis carinii Preparation (if tissue specimen)

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Poliovirus Antibody Profile		Test Code: POVA
Includes:	Poliovirus 1, 2 and 3 Antibodies
CPT:	86658 for each (x3)
Methodology:	Complement Fixation
Testing Schedule:	Routine, 3 times per week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
<1:8....Antibody not detected.
Clinical Utility:
Because CF antibody levels usually persist for only a few months, any measurable titer may indicate recent exposure. Single titers 132 provide strong evidence for recent exposure. A four-fold or greater increase in titer between acute and convalescent specimens confirms recent exposure orinfection.

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Poliovirus Antibody, Vaccine Response		Test Code: POLVR
Includes:	Poliovirus 1, 2 and 3 Antibodies
CPT:	86382 (x3)
Alternate Name:	• Poliovirus Ab • Vaccine response • Polio Ab
Methodology:	Viral Antibody Neutralization
Testing Schedule:	Routine, 1 time per week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate Please note if specimens are pre- or post-vaccination.
Reference Range:
See report.
Clinical Utility:
The presence of neutralizing serum antibodies (titers 1:8 or greater) against polioviruses implies lifelong immunity. The serum neutralization test is type specific; antibodies detected against one type does not indicate immunity against other types. However, some persons without detectable titers (< 1:8) may also be immune. This has been demonstrated by elicitation of a secondary-type serum antibody response upon rechallenge with live polio vaccine.

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Poliovirus Antibody Viral Neutralization
See Poliovirus Antibody, Vaccine Response

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Polymositis-Scleroderma Antibody
See PM/Scl AutoantibodyPork Tapeworm
See Parasite Identification

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Porphobilinogen, Random Urine		Test Code: PORPU
CPT:	84110
Methodology:	Liquid Chromatograph /Tandem Mass Spectrometry (LC-MS/MS) 3 table Isotope Dilution Analysis
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	20 mL random urine
Container:	Plastic 60 mL amber urine bottle or sterile plastic urine cup.
Special Instructions and/or Comments:
•Send specimen frozen in a plastic urine container. Once frozen, transport specimen submerged in dry ice. •Protect from light by wrapping the entire bottle with aluminum foil.
Reference Range:
< 1.3 mcmol/L
Clinical Utility:
Useful for, first-line test for establishing a tentative diagnosis for acute neuropathic porphyria including acute intermittent porphyria (AIP), hereditary coproporphyria (HCP), and variegate porphyria (VP).

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Porphyrins, Quantitative, 24-Hour Urine		Test Code: POPH
Includes:	• Volume Measurement • Collection Period • Uroporphyrin • Heptacarboxylporphyrin • Hexacarboxylprophyrin • Pentacarboxylporphyrin • Coproporphyrin • Porphobilinogen
CPT:	81050, 84110, 84120
Methodology:	High Performance Liquid Chromatography (HPLC) with Fluorometric Detection and Liquid Chromatography-tandem mass spectrometry (LC-MS/MS) for porphobilinogen
Testing Schedule:	Routine, Monday-Friday ONLY
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	25-50 mL aliquot of a well mixed 24-Hour urine collection
Container:	24-Hour plastic urine container. Add 5 g of Na2CO3 at beginning of collection.
Collection:	•Instruct the patient to void at the beginning of the collection period and discard the specimen. •Collect all urine, including the final specimen voided at the end of collection period. •Refrigerate during collection. •Container must be labeled with the patient’s name.
Special Instructions and/or Comments:
•Instruct patient not to void directly into container. •Protect from light by wrapping the entire container with aluminum foil. •Transport to the laboratory promptly. •Requisition must state date and time collection began and date and time collection was completed.
Reference Range:
•Uroporphyrin................................... < 30 nmol/24 hrs •Heptacarboxylporphyrin.................. < 9 nmol/24 hours •Hexacarboxylporphyrin................... < 8 nmol/24 hours •Pentacarboxylporphyrin .................. < 10 nmol/24 hours •Coproporphyrin •Males.................. < 230 nmol/24 hours •Females.............. < 168 nmol/24 hours •Porphobilinogen.............. < 2.2 mcmol/24 hours
Clinical Utility:
The measurement of PBG is important in the diagnosis of acute, neurologic porphyrias including acute intermittent porphyria (AIP), hereditary coproporphyria (HCP), and variegate porphyria (VP). Urinary porphyrin determination is helpful in the diagnosis of these disorders, as well as other porphyrias including congenital erythropoietic porphyria (CEP) and porphyria cutanea tarda (PCT).

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Postbronchoscopy Sputum
See Cytopathology, Sputum Series

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Postmortem Examination
See Histopathology, Autopsy

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Potassium, Body Fluid		Test Code: FK
CPT:	84999
Alternate Name:	Body Fluid K; Body Fluid Potassium; K, Body Fluid
Methodology:	Potentiometry
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL body fluid
Container:	Red top tube, no serum separator
Special Instructions and/or Comments:
Requisition must state site of specimen.
Reference Range:
Not established, must be interpreted with clinical findings.

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Potassium, Serum		Test Code: K
CPT:	84132
Alternate Name:	K+; K, Blood; Serum Potassium
Methodology:	Potentiometry
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
•Transport to the laboratory immediately. •If testing cannot be performed within 4 hours of collection, centrifuge, transfer to plastic aliquot tube and refrigerate.
Reference Range:
•<11 days:................3.7-5.9 mEq/L • >11 days................3.5-5.2 mEq/L
Critical Values:
•<3.0 mEq/L •>6.0 mEq/L
Clinical Utility:
Used to evaluate electrolyte and acid/base balance,cardiac arrhythmias, diuretic therapy and renal conditions.

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Potassium Hydroxide Preparation
See KOH/Calcofluor Prep

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Potassium, Urine 24-Hour		Test Code: 24K
Includes:	Volume Measurement Collection Period Creatinine, Urine Potassium, Urine
CPT:	84133, 81050
Alternate Name:	K+, Urine; Urine K+
Methodology:	Potentiometry and Two-point Rate
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	Entire 24-Hour urine collection
Container:	Entire 24-Hour plastic urine container, no preservative
Special Instructions and/or Comments:
Transport to the laboratory promptly.
Clinical Utility:
Used to evaluate electrolyte and acid base balance and hypokalemia.

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PR3 Autoantibody
See Neutrophil Cytoplasmic Autoantibody Profile

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Prealbumin		Test Code: PREA
CPT:	84134
Methodology:	Rate Nephelometry
Testing Schedule:	Routine, daily
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
21-41 mg/dL
Clinical Utility:
Assess protein nutritional status; evaluate total parenteral nutrition

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Potassium, Urine Random		Test Code: RUK
CPT:	84133
Alternate Name:	K+, Urine; Urine K+
Methodology:	Potentiometry
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Collection:	Random
Special Instructions and/or Comments:
Transport to the laboratory promptly.
Reference Range:
20-125 mEq/L
Clinical Utility:
Used to evaluate electrolyte and acid base balance and hypokalemia.

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PR3 Autoantibody
See Neutrophil Cytoplasmic Autoantibody Profile

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Pregnancy Test
See Beta Human Chorionic Gonadotropin, Serum See Beta Human Chorionic Gonadotropin, Urine

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Prekallikrein		Test Code: PREK
CPT:	85292
Alternate Name:	Fletcher Factor
Methodology:	Clot Based Assay
Testing Schedule:	Routine, 1 time per week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	2 mL plasma, split equally into 2 plastic aliquot tubes and FROZEN immediately
Container:	2 Blue top (sodium citrate) tubes
Collection:	See special handling instructions for “Coagulation Studies”, listed under Specimen Collection, Preparation, and Handling Section
Special Instructions and/or Comments:
•Testing is contraindicated for patients on Heparin or Coumadin® therapy. •Immediately centrifuge at 1500-1700 X G for 10 minutes.Avoiding the buffy coat, carefully remove the plasma from the cells using a plastic pipette.Aliquot the plasma into the required number of plastic aliquot tubes and label with “citrated plasma” labels. •Freeze the aliquoted specimens at –40° to –60°C.Once frozen, transport the specimens submerged in dry ice. Causes for rejection •Extended transport time to laboratory •Clotted specimens •Hemolyzed specimens •Blue top sodium citrate tubes insufficiently filled •Aliquots not received frozen on dry ice •Frozen aliquots not clearly identified as “citrated plasma”
Reference Range:
65-135%
Clinical Utility:
Useful for explaining a prolonged PTTwhen all other coagulation factors are present in normal percentages.

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Prenatal Package 1 (No Urinalysis)
See Obstetric Panel

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Prenatal Package 2 (Includes Urinalysis)
See Obstetric Profile with Urinalysis

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Prenatal Screen
See Obstetric Profile, Repeat Blood Bank Only

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Prenatal Testing, Repeat Blood Bank Only
See Obstetric Profile, Repeat Blood Bank Only

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Primidone		Test Code: MYSL
Includes:	•Primidone •Phenobarbital metabolite
CPT:	80188, 80184
Alternate Name:	Mysoline®
Methodology:	Immunoassay (IA)
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Reference Range:
Therapeutic •Primidone 5.0-12.0µg/mL •Phenobarbital 15-40µg/mL
Clinical Utility:
Useful for monitoring therapy and assessing toxicity.

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Procainamide		Test Code: PROC
Includes:	• Procainamide • N-acetylprocainamide (NAPA)
CPT:	80192
Alternate Name:	• Pronestyl® • NAPA • Acetylprocainamide
Methodology:	Immunoassay (IA)
Testing Schedule:	Routine
Report Available:	2-3 days
Specimen Requirements:
Minimum Volume:	1.0 mL serum (0.4mL minimum)
Container:	Red top tube, no serum separator
Reference Range:
Therapeutic •Procainamide......................................4-8 µg/mL •Sum of procainamide + NAPA..........<30 µg/mL
Clinical Utility:
Useful for monitoring therapy and assessing toxicity.

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Progesterone, 17-Alpha-Hydroxy
See 17-Hydroxyprogesterone

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Progesterone, Serum		Test Code: PGTR
CPT:	84144
Methodology:	Direct Chemiluminescence
Testing Schedule:	Routine, STAT testing available 0600-2100
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
•Testing must be performed within 8 hours of collection. •If delay in transport centrifuge, transfer to plastic aliquot tube and refrigerate tube in the upright position.Specimen should remain capped until time of testing.
Reference Range:
Normal Females • Follicular Phase........... 0.15-1.40 ng/mL • Luteal Phase.................3.34-25.56 ng/mL • Mid-Luteal Phase.........4.44-28.03 ng/mL Pregnant Female • First Trimester.............11.22-90.00 ng/mL • Second Trimester.........25.55-89.40 ng/mL • Third Trimester...........48.40-422.50 ng/mL Postmenopausal:..............< 0.74 ng/mL Males:............................... 0.28-1.22 ng/mL
Clinical Utility:
Used in the evaluation of infertility, ovulation and to monitor the success of induced ovulation.

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Progressive Systemic Sclerosis Antibody
See Scl-70 Autoantibody

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Proinsulin		Test Code: PROIN
CPT:	84206
Methodology:	Immunochemiluminescent Assay
Testing Schedule:	Routine, 2 times per week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	1.5 mL EDTA plasma
Container:	Prechilled lavender top (EDTA) tube
Collection:	Overnight fast required.
Special Instructions and/or Comments:
•Transport to the laboratory immediately. •Must be processed and frozen immediately. •Centrifuge, transfer to plastic aliquot tube and freeze.Once frozen, transport specimen submerged in dry ice.
Reference Range:
3-20 pmol/L
Clinical Utility:
Diagnosis of insulinoma.

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Prolactin, Serum		Test Code: PLTN
CPT:	84146
Methodology:	Direct Chemiluminescence
Testing Schedule:	Routine, STAT testing available 0600-2100
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube,
Special Instructions and/or Comments:
•Testing must be performed within 8 hours of collection. •If delay in transport, centrifuge, transfer to plastic aliquot tube and refrigerate tube in the upright position. Specimen should remain capped until time of testing.
Reference Range:
Females • Non-pregnant:.................2.8-29.2 ng/mL • Pregnant:.........................9.7-208.5 ng/mL • Postmenopausal..............1.8-20.3 ng/mL Males2.1-17.7 ng/mL
Clinical Utility:
Used in the evaluation of infertility, amenorrhea,galactorrhea, pituitary tumors and in the monitoring of prolactinoma treatment.

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Prolan A
See Follicle Stimulating Hormone,Serum

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Prolixin®
See Fluphenazine

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Pronestyl®
See ProcainamideProperdin Factor B
See Complement, C3 Proactivator

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Propoxyphene, Qualitative, Urine		Test Code: PPXP
Includes:	Identification of propoxyphene and/or metabolite norpropoxyphene
CPT:	80101
Alternate Name:	Darvocet-N®; Darvon®
Methodology:	Immunoassay (IA)
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL urine
Container:	Plastic urine container
Special Instructions and/or Comments:
If for forensic or legal purposes, submit specimen with a completed Drug Testing Request and Chain-of-Custody (HNL-53) Form or Blood Alcohol Toxicology Request/Chain-of-Custody (LAB-53) Form in plastic evidence bag.
Reference Range:
None detected NOTE Confirmation by GC/MS (gas chromatography/mass spectrometry) available upon request.Contact Customer Care 610-402-8170 for instructions.
Clinical Utility:
A qualitative screen useful for detection of drug abuse/use of propoxyphene.Confirmation of a positive screening result by GC/MS is strongly recommended.

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Propoxyphene, Quantitative, Blood		Test Code: BPOXY
Includes:	Identification and quantitation of propoxyphene and norpropoxypheneby
CPT:	82542
Methodology:	Gas Chromatography-Mass Spectroscopy
Testing Schedule:	Once/week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mL whole blood
Container:	1 gray top or lavendar top
Reference Range:
Therapeutic range for Propxyphene + Norpropoxyphene is 1.0-3.7 ug/mL
Clinical Utility:
To determine blood level of propoxyphene to determine toxicity or overdose.

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Propranolol		Test Code: PROP
CPT:	80299
Alternate Name:	Inderal®
Methodology:	High performance Liquid Chromatography (HPLC))
Testing Schedule:	Routine, 1 time per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Red top tube, no serum separator
Collection:	Optimum time to collect trough specumens is just prior to the next dose. Patient should refrain from taking propafenone (Rythmol) one week prior to specimen collection
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Therapeutic Concentration.....................30-100 ng/mL
Clinical Utility:
Useful for monitoring compliance.

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Propoxyphene, Urine, GCMS		Test Code: GCUX
Includes:	Identification and quantitation of propoxyphene and norpropoxypheneby GCMS
CPT:	82542
Methodology:	Gas Chromatography/Mass Spectroscopy (GC/MS)
Testing Schedule:	3 times/week
Report Available:	2-4 days
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Special Instructions and/or Comments:
If for forensic or legal purposes, submit specimen with a completed Drug TestingRequest and Chain-of-Custody (HNL-53) Formor Blood Alcohol Toxicology Request/Chain-of-Custody (LAB-32) Form.
Reference Range:
None present
Clinical Utility:
Useful for the detection and positive identification of propoxyphene and norpropoxyphene in urine.

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Prostate Specific Antigen, Free and Total		Test Code: FPSAG
Includes:	Prostate Specific Antigen, Total Prostate Specific Antigen, Free Prostate Specific Antigen, % Free (calculation)
CPT:	84153, 84154
Alternate Name:	Free PSA
Methodology:	Chemiluminescent Microparticle Immunoassay (CMIA)
Testing Schedule:	Routine, 3 times per week
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
• Must be processed and frozen within 24 hours of collection. • Centrifuge, transfer to plastic aliquot tube, transport specimen refrigerated.
Reference Range:
Prostate Specific Antigen, Total............... <4.00 ng/mL Prostate Specific Antigen, Free.................N/A Prostate Specific Antigen, % Free See “Interpretation Chart” below % Free PSA Interpretation* % Free PSA Value Probability of Prostate Cancer <10% 67.9% 10-15% 50.0% 15-20% 32.1% 20-26% 18.3% >26% 9.6% *Please note that the clinical utility of % Free PSA has not been determined for values <4.00 or >10.00 ng/mL.
Clinical Utility:
Testing is best utilized as a follow up on patients previously determined to have Total PSA values in the range of 4.00-10.00 ng/mL. In this range, the measurement of Free PSA and the calculation of a % Free PSA value are helpful in the discrimination of prostate cancer from benign disease.

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Prostate Specific Antigen, Total		Test Code: PSAGT
CPT:	84153
Alternate Name:	PSA; PSAG; PSA Screen
Methodology:	Chemiluminescent Microparticle Immunoassay (CMIA)
Testing Schedule:	Routine, daily
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
•If specimen cannot be tested within 72 hours, centrifuge, transfer to plastic aliquot tube and freeze.Once frozen, transport specimen submerged in dry ice. •It is recommended to obtain specimens for PSA testing prior to procedures involving manipulation of the prostate.In most instances specimens obtained from patients immediately following digital rectal examination (DRE) show no clinically significant elevations in PSA levels.However, prostatic massage, ultrasonography and needle biopsy may cause clinically significant elevations. PSA levels may also be increased following ejaculation. •The concentration of PSA in a given specimen, determined with assays from different manufacturers, can vary due to differences in assay methods, calibration, and reagent specificity. •When monitoring a patient sequentially for cancer management, the same assay should be consistently utilized. •Avoid palpation of the prostate for 2 weeks prior to testing. Rectal examination within 48 hours of specimen collection may cause elevation of results.
Reference Range:
<4.00 ng/mL
Clinical Utility:
Determination of Total PSA levels are useful asAn aid in the detection of prostate cancer when used in conjunction with digital rectal examination (DRE) in men 50 years or older. An adjunctive test to aid in management of prostate cancer patients.

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Prostate Specific Antigen, Total, Screen		Test Code: PSAST
CPT:	84153, G0103
Alternate Name:	PSA; PSAG; PSA Screen
Methodology:	Chemiluminescent Microparticle Immunoassay (CMIA)
Testing Schedule:	Routine, daily
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
•If specimen cannot be tested within 72 hours, centrifuge, transfer to plastic aliquot tube and freeze.Once frozen, transport specimen submerged in dry ice. •It is recommended to obtain specimens for PSA testing prior to procedures involving manipulation of the prostate.In most instances specimens obtained from patients immediately following digital rectal examination (DRE) show no clinically significant elevations in PSA levels.However, prostatic massage, ultrasonography and needle biopsy may cause clinically significant elevations. PSA levels may also be increased following ejaculation. •The concentration of PSA in a given specimen, determined with assays from different manufacturers, can vary due to differences in assay methods, calibration, and reagent specificity. •When monitoring a patient sequentially for cancer management, the same assay should be consistently utilized. •Avoid palpation of the prostate for 2 weeks prior to testing. Rectal examination within 48 hours of specimen collection may cause elevation of results.
Reference Range:
<4.00 ng/mL
Clinical Utility:
Determination of Total PSA levels are useful asAn aid in the detection of prostate cancer when used in conjunction with digital rectal examination (DRE) in men 50 years or older. An adjunctive test to aid in management of prostate cancer patients.

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Prostate Specific Antigen, Total, with Reflex PSA, Free		Test Code: PSAR
Includes:	•Prostate Specific Antigen, Total •Reflexed on Total PSA values in the range of 4.00-10.00 ng/mL •Prostate Specific Antigen, Free •Prostate Specific Antigen, % Free (calculation)
CPT:	84153 Reflexed when appropriate 84154
Methodology:	Chemiluminescent Microparticle Immunoassay (CMIA)
Testing Schedule:	Routine, 3 times per week
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
•Must be processed and frozen within 24 hours of collection. •Centrifuge, transfer to plastic aliquot tube and freeze. Once frozen, transport specimen submerged in dry ice.
Reference Range:
Prostate Specific Antigen, Total................... <4.00 ng/mL Prostate Specific Antigen, Free.....................N/A Prostate Specific Antigen, % Free See “Interpretation Chart” below % Free PSA Interpretation* % Free PSA Value Probability of Prostate Cancer <10% 67.9% 10-15% 50.0% 15-20% 32.1% 20-26% 18.3% >26% 9.6% *Please note that the clinical utility of % Free PSA has not been determined for Total PSA values <4.00 or >10.00 ng/mL.
Clinical Utility:
In patients not previously diagnosed with prostatic cancer, Total PSA screening values in the range of 4.00-10.00 ng/mL warrant further testing as an aid in discriminating between prostate cancer and benign disease. Reflex testing with a Free PSA assay and the calculation of a % Free PSA value may improve the discrimination in men with intermediate levels of Total PSA and non-suspicious digital rectal examination (DRE).

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Prostatic Acid Phosphatase
See Acid Phosphatase, Prostatic

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Prostatic Fluid Culture
See Culture, Genital
See Culture, Fluid, Aerobic

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Protein Bound Glucose
See FructosamineProtein C
See Protein C, Functional

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Protein C, Functional		Test Code: PRNC
CPT:	85303
Alternate Name:	Protein C
Methodology:	Clot Based Assay
Testing Schedule:	Routine, 1 time per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mL prepared “platelet poor plasma” split equally into 2 plastic aliquot tubes and FROZEN immediately.
Container:	2 Blue top (sodium citrate) tubes
Collection:	See special handling instructions for “Coagulation Studies”, listed under Specimen Collection, Preparation, and Handling
Special Instructions and/or Comments:
•Testing is contraindicated for patients on Heparin or Coumadin therapy. •Preparation and submission of “platelet poor plasma” is critical for accurate test performance and interpretation.See collection note above. Causes for rejection •Extended transport time to laboratory •Clotted specimens •Hemolyzed specimens •Blue top sodium citrate tubes insufficiently filled •Aliquots not received frozen on dry ice •Frozen aliquots not clearly identified as “platelet poor plasma”
Reference Range:
77% to 145%
Clinical Utility:
Protein C deficiency can lead to thrombotic complications. Acquired Protein C deficiency is noted in coumadin therapy, DIC, acute thromboembolic disease, severe liver disease, hemolytic uremic syndrome and in TTP.

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Protein, Cerebrospinal Fluid		Test Code: CSFP
CPT:	84157
Alternate Name:	Cerebrospinal Fluid Protein; CSF Protein; Protein, CSF
Methodology:	Endpoint
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	0.5 mL cerebrospinal fluid
Container:	Sterile conical tube
Special Instructions and/or Comments:
• Testing should be performed on tube #1. • Tubes must be numbered indicating the sequence of collection.
Reference Range:
• <1 month.....................30-170 mg/dL • >1 month:...................30-100 mg/dL • >7 months..................12-60 mg/dL
Critical Values:
>75 mg/dL
Clinical Utility:
Used in the evaluation of infection, inflammation, trauma, malignancy and other disorders of the central nervous system.

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Protein/Creatinine Ratio, Random Urine		Test Code: CALTC
Includes:	Creatinine, Urine Protein, Total, Urine
CPT:	82570, 84156
Methodology:	See individual test listings
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Reference Range:
• Protein, Total, Random Urine..............<12 mg/dL • Creatinine, Random Urine..................50-200 mg/dL • Ratio<0.15
Clinical Utility:
Used to evaluate proteinuria and renal disorders.

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Protein, CSF
See Protein, Cerebrospinal Fluid

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Protein Electrophoresis, Cerebrospinal Fluid		Test Code: CSFE
CPT:	84157, 84166
Alternate Name:	•CSF Electrophoresis •Electrophoresis, Protein, CSF
Methodology:	Agarose Gel Electrophoresis, Spectrophotometry
Testing Schedule:	Routine, daily
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	3 mL cerebrospinal fluid
Container:	Sterile conical tube
Reference Range:
•Protein CSF...............................15 to 45 mg/dL •Prealbumin CSF..........................2 to 7 % •Albumin CSF............................57 to 76 % •Alpha1 CSF................................1 to 7 % •Alpha2 CSF................................3 to 13 % •Beta CSF....................................7 to 18 % •Gamm CSF.................................3 to 13 % Report includes an interpretation
Clinical Utility:
Useful in the evaluation of meningitis,tuberculosis, brain abscess, meningovascular syphilis, CVA, neoplastic disease, multiple sclerosis, and other degenerative processes causing neurological disease.

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Protein Electrophoresis, Serum		Test Code: SPRE
Includes:	•Protein, Total, Serum •Quantitations of Albumin, Alpha-1, Alpha-2, Beta and Gamma Fractions •Scan with Pathologist’s Interpretive Report •Serum IEP/IFE Profile is performed if abnormal results are observed on the SPEPscreen
CPT:	84155 , 84165 Reflexed when appropriate 82784 (x3), 86334
Alternate Name:	Electrophoresis, Serum; Serum Protein Electrophoresis; SPE; SPEP
Methodology:	Agarose Gel Electrophoresis
Testing Schedule:	Routine, 3-5 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
•Testing is contraindicated on hemolyzed or grossly lipemic specimens. •Plasma specimens are unacceptable.
Reference Range:
•Total protein.....................6.0-8.0 g/dL •Albumin...........................3.2-4.2 g/dL •Alpha1 region..................0.1-0.4 g/dL •Alpha2 region..................0.7-1.1 g/dL •Beta region......................0.8-1.3 g/dL •Gamma region.................0.7-1.7 g/dL
Clinical Utility:
Useful for chronic active hepatitis; useful in the evaluation of myeloma, macroglobulinemia of Waldenstrom, collagen diseases, and monoclonal gammopathies; evaluate inflammatory states; evaluate low back pain, arthritis, amyloidosis; evaluate lymphoma, leukemia, anemia.

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Protein Electrophoresis, Urine		Test Code: UPRE
Includes:	•Scan with Pathologist’s Interpretive Report •Urine IEP/IFE Profile is performed if abnormal results are observed on the UPEP screen
CPT:	84166 Reflexed when appropriate 86335
Alternate Name:	Bence Jones Protein; BJP; Electrophoresis, Protein, Urine; Globulins, Urine; UPE; UPEP; Urine Electrophoresis; Urine Protein Electrophoresis
Methodology:	Agarose Electrophoresis Gel
Testing Schedule:	Routine, 3-5 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	20-40 mL random urine OR 20-40 mL aliquot of a well- mixed 24-Hour urine collection ContainerPlastic urine container OR 24-Hour plastic urine container, no preservative
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Negative no protein present; no suggestion of monoclonal free light chains (Bence Jones protein).

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Protein S
See Protein S, Functional

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Protein S, Functional		Test Code: PRNS
CPT:	85306
Alternate Name:	Protein S
Methodology:	Clot Based Assay
Testing Schedule:	Routine, 1 time per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mL prepared “platelet poor plasma” split equally into 2 plastic aliquot tubes and FROZEN immediately.
Container:	2 Blue top (sodium citrate) tubes
Collection:	See special handling instructions for “Coagulation Studies”, listed under Specimen Collection, Preparation, and Handling Section
Special Instructions and/or Comments:
•Testing is contraindicated for patients on Heparin or Coumadin therapy. •Preparation and submission of “platelet poor plasma” is critical for accurate test performance and interpretation.See collection note above. Causes for rejection •Extended transport time to laboratory •Clotted specimens •Hemolyzed specimens •Blue top sodium citrate tubes insufficiently filled •Aliquot not received frozen on dry ice •Frozen aliquots not clearly identified as “platelet poor plasma”
Reference Range:
70% to 125%
Clinical Utility:
Hereditary protein S deficiency is associated with recurrent venous thromboembolic disease often presenting in adolescents or young adults. Protein Slevels are low in pregnancy and coumadin therapy. Acquired Protein S deficiency is documented in DIC, Type I and II diabetes mellitus, pregnancy, oralcontraceptive use, nephrotic syndrome, liver disease, and essential thrombocythemia.

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Protein, Total, Body Fluid		Test Code: FTP
CPT:	84157
Alternate Name:	Body Fluid Protein
Methodology:	Endpoint
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL body fluid
Container:	Red top tube, no serum separator
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Not established, must correlate with clinical findings. NOTE Pleural fluid Transudate.............<3 g/dL Pleural fluid Exudate..................>3 g/dL
Clinical Utility:
To aid in the evaluation of effusions and to help differentiate exudates from transudates.

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Protein, Total, Serum		Test Code: TP
CPT:	84155
Alternate Name:	Total Protein, Blood
Methodology:	HNL Endpoint LPP Bichromatic endpoint
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
• <1 month:..................4.6-7.0 g/dL •>1 month:...................4.5-6.5 g/dL •>6 months:.................5.4-7.5 g/dL •>2 years:....................5.3-8.0 g/dL •>16 years ...................6.3-8.2 g/dL
Clinical Utility:
Used to evaluate nutritional status, edema, hepatic, renal and other protein altering disorders.

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Protein, Total, Urine Random		Test Code: RUTP
CPT:	84156
Alternate Name:	Quantitative Urine Protein; Total Protein, Urine; Urine Protein
Methodology:	Endpoint
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Collection:	Random
Reference Range:
<12 mg/dL
Clinical Utility:
Used to evaluate proteinuria and monitor kidney function.

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Protein, Total, Urine24-Hour		Test Code: 24TP
Includes:	•Volume Measurement •Collection Period •Creatinine, Urine •Protein, Total, Urine
CPT:	81050, 84156
Alternate Name:	Quantitative Urine Protein; Total Protein, Urine; Urine Protein
Methodology:	Endpoint
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	Entire 24-Hour urine collection
Container:	Entire 24-Hour plastic urine container, no preservative
Collection:	24-Hour urine collection See special instructions for “24-Hour Urine Collection”, listed under Specimen Collection, Preparation, and Handling Section
Special Instructions and/or Comments:
Transport to the laboratory promptly.
Reference Range:
•Creatinine, 24-Hour Urine...........0.8-2.8 g/24 hours •Protein, 24-Hour Urine................0.04-0.23 g/24 hours
Clinical Utility:
Used to evaluate proteinuria and monitor kidney function.

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Prothrombin (Factor II) Mutation
See Prothrombin Gene Mutation, G20210A

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Prothrombin Fragment 1 & 2		Test Code: PROFR
CPT:	83520
Methodology:	Enzyme-Linked Immunosorbent Assay (ELISA)
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mL frozen plasma split equally into 2 plastic aliquot tubes and FROZEN immediately.
Container:	2 Blue top (sodium citrate) tubes
Collection:	See special handling instructions for “Coagulation Studies”, listed under Specimen Collection, Preparation, and Handling Section
Special Instructions and/or Comments:
•Testing is contraindicated for patients on Heparin or Coumadin therapy. •Immediately centrifuge at 1500-1700 X G for 10 minutes.Avoiding the buffy coat, carefully remove the plasma from the cells using a plastic aliquot pipette.Aliquot the plasma into the required number of plastic aliquot tubes and label with “cirated plasma” labels. •Freeze the aliquoted specimens at –40 to –60°C. Once frozen, transport the specimens submerged in dry ice. Causes for rejection •Extended transport time to laboratory •Clotted specimens •Hemolyzed specimens •Blue top sodium citrate tubes insufficiently filled •Aliquots not received frozen on dry ice •Frozen aliquots not clearly identified as “citrated plasma”
Reference Range:
87-325 pmol/L
Clinical Utility:
This test assesses ongoing coagulation.Activation as may occur in thrombosis and DIC.

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Prothrombin Gene Mutation G20210A		Test Code: PGENE
CPT:	83890; 83896 (X2); 83898; 83912
Alternate Name:	Factor II Mutation, DNA 20210; Prothrombin (Factor II) Mutation
Methodology:	Realtime PCR
Testing Schedule:	Routine 2x per week
Report Available:	1-3 working days
Specimen Requirements:
Minimum Volume:	5 mL whole blood
Container:	1 Full Lavender top [EDTA] tube
Special Instructions and/or Comments:
•Store as whole blood in original tube. •Refrigerate at 2-8C only. •DO NOT centrifuge, aliquot or freeze. •Heparin specimen NOT acceptable
Reference Range:
Not Detected.
Clinical Utility:
Useful in detecting the Promthrombin G20210A Mutation for the evaluation of thrombotic risk.

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Prothrombin Time (PT) Profile		Test Code: PTPR
Includes:	• PT • PT mixing study reflexed when appropriate • Thrombin Time (TT) reflexed when appropriate • Reptilase Time (REPTL) reflexed when appropriate
CPT:	85610, Reflexed when appropriate, 85611, 85670, 85635
Alternate Name:	PT mixing study; PT Profile
Methodology:	Mechanical Clot Detection
Testing Schedule:	Routine, Monday-Friday only
Report Available:	2-3 days
Specimen Requirements:
Minimum Volume:	5 mL citrated plasma
Container:	4 full Blue top (sodium citrate) tubes
Collection:	See special handling instructions for “Coagulation Studies”, listed under Specimen Collection, Preparation, and Handling Section
Special Instructions and/or Comments:
• Testing is contraindicated for patients on heparin or Coumadin therapy. • Transport to the laboratory immediately. • If testing cannot be performed within 4 hours of collection, platelet pour plasma must be prepared prior to freezing. • Immediately centrifuge specimens at 1700 to 2000 g for 10 minutes • Remove the plasma and dispense into plastic aliquot tube. Spin aliquot for 10 minutes. • Remove the plasma and dispense into another plastic aliquot tube. Spin new aliquot for 10 minutes. Transfer plasma into 8 aliquot tubes and freeze. • Once frozen, specimens should be submerged in dry ice for transport..
Reference Range:
See report.
Critical Values:
PT.............>45.7 seconds* INR...........>4.9 * Value varies with reagent lot
Clinical Utility:
A PT mixing study can differentiate between a coagulation factor deficiency or the presence of an inhibitor.

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Prothrombin Time with INR, Plasma		Test Code: PTP
Includes:	• Prothrombin Time (PT) INR (international normalized ratio) • INR (International Normalized Ratio)
CPT:	85610
Alternate Name:	Protime; PT
Methodology:	Mechanical Clot Detection
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL citrated plasma
Container:	Full blue top (sodium citrate) tube
Collection:	See special handling instructions for “Coagulation Studies”, listed under Specimen Collection, Preparation,and Handling Section
Special Instructions and/or Comments:
•Unopened (capped) tubes, uncentrifuged, or centrifuged, stored at 18-24.C (room temperature) and tested within 24 hours are acceptable. • If testing cannot be performed within 24 hours of collection, centrifuge the specimen at 3000 rpm for 15 minutes (5000 rpm for 5 minutes if using a hettich centrifuge), and transfer the plasma to a plastic aliquot tube and freeze. Once frozen, transport the specimen submerged in dry ice. •If plasma is not separated and frozen, testing cannot be added on to existing orders if it is more than 24 hours past the specimen draw time. If plasma is frozen, testing can be added.
Reference Range:
*Range/value varies with reagent lot. HNL.................12.0 - 14.2 seconds* LPP................. 11.0 - 13.7 seconds*
Critical Values:
* Range varies with reagent lot HNL PT.......> 49.1 seconds* INR.. ..> 4.9 LPP PT.......> 27.3 seconds* INR.... > 4.9 Clinical Condition INR Ambulatory Surgery < 1.5 Coumadinized Patients DVT, PE, MI, or A.Fib............2.0 - 3.0 Mechanical Heart Valve..........2.5 - 3.5 Cardiogenic Embolus..............2.5 - 3.5
Clinical Utility:
Used in the evaluation of the extrinsic coagulation system and in coagulation disorders / deficiencies. Also used in monitoring warfarin Coumadin® therapy.

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Protime
See Prothrombin Time with INR, Plasma

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Protoporphyrin, Zinc, Blood		Test Code: ZPP
CPT:	84202
Alternate Name:	Zinc Protoporphyrin
Methodology:	Hematofluorometry
Testing Schedule:	Routine, 2 times per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	1 mL whole blood
Container:	Lavender top (EDTA) tube OR dark blue (EDTA or heparin) tube
Special Instructions and/or Comments:
•Store as whole blood in original tube. •DO NOT centrifuge, aliquot, refrigerate or freeze. •Protect from light by wrapping the entire tube with aluminum foil.
Reference Range:
<35 .µg/dL

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Prozac®
See Fluoxetine

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PSA
See Prostate Specific Antigen, Total OR Prostate Specific Antigen, Total, Screen

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PSAG
See Prostate Specific Antigen, Total OR Prostate Specific Antigen, Total, Screen

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PSA Screen
See Prostate Specific Antigen, Total OR Prostate Specific Antigen, Total, Screen

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PSAT
See Total Iron Binding Capacity Profile

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Pseudocholinesterase, Serum		Test Code: PCHE
CPT:	82480
Alternate Name:	Cholinesterase, Blood
Methodology:	Spectrophotography
Testing Schedule:	Routine, Daily
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
Female:.............2673-6592 IU/L Male:.................3342-7586 IU/L
Clinical Utility:
Patients exposed to organophosphorus compounds exhibit decreased levels of cholinesterase. A 30-50% decrease is observed in acute hepatitis and chronic hepatitis of long duration. 50-70% decreases occur in advanced cirrhosis and carcinoma with metastases to the liver. Cholinesterase measurements are also used in the detection of patients with inherited abnormal variants of the enzyme.

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Pseudomembranous Colitis Toxin Assay
See Clostridium difficile Toxin A/B Assay

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PT
See Prothrombin Time with INR, Plasma

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PTH Related Protein
See Parathyroid Hormone Related Peptide

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PTHRP
See Parathyroid Hormone Related Peptide

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PTT
See Partial Thromboplastin Time, Activated, Plasma

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Pulmonary Cytology Series
See Cytopathology, Sputum Series

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Purkinje Cell Antibody (PCA-1)
See Yo Autoantibody

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Pus Culture
See Culture, Wound, Aerobic

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Pyruvate		Test Code: PYRU
CPT:	84210
Alternate Name:	Pyruvic Acid
Methodology:	Spectrophotometry
Testing Schedule:	Routine, 3 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL whole blood added to special prechilled collection tube
Container:	Prior to collecting specimen, contact our Referral Testing Department at 610-402-5864 for a special prechilled collection tube containing 2.5 mL 6% perchloric acid into which blood will be transferred.
Collection:	Collect enough blood directly into syringe to add exactly 1.0 mL of blood to the special prechilled collection tube.
Special Instructions and/or Comments:
•Once drawn, immediately transfer 1.0 mL of blood to the special collection tube. •Shake vigorously to mix. •Transport to the laboratory refrigerated in the special collection tube. •DO NOT centrifuge, aliquot or freeze.
Reference Range:
0.7 - 1.4 mg/dL
Clinical Utility:
Pyruvate, in conjunction with lactate determined from a blood specimen collected at the same time, is used to assess the L/P ratio. The L/P ratio is considered a helpful (not diagnostic) tool in the evaluation of patients with possible disorders of mitochondrial metabolism. Pyruvic acid levels alone have little clinical utility.

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Pyruvic Acid
See Pyruvate