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M. pneumoniae Titer
See Mycoplasma pneumoniae Antibody Profile

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M. tb PCR
See Mycobacterium tuberculosis, PCR,Cerebrospinal Fluid

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Macroscopic Examination, Urine
See Urinalysis with Reflex Microscopic

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MAG Antibody Dual ELISA
See MAG Antibody Profile

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MAG Antibody Profile		Test Code: MAGDT
Includes:	•SGPG IgM Antibody •MAG IgM Antibody •MAG Western Blot (WB) will be performed on specimens positive in either or both ELISAs.
CPT:	83520 (X2)
Alternate Name:	MAG Antibody Dual ELISA; Myelin Associated Glycoprotein Autoantibody
Methodology:	Enzyme-Linked Immunosorbent Assay (ELISA)
Testing Schedule:	Routine, 3 times per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	2 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
•SGPG IgM Antibody <1.00 No antibody detected. •MAG IgM Antibody <1.00 No antibody detected. •MAG Antibody, Western blot Negative Interpretative Criteria: < 1.00 Antibody Not Detected > 1.00 Antibody Detected
Clinical Utility:
Detection of MAG antibodies is associated with sensorimotor neuropathies. Markedly elevated levels are seen predominantly in demyelinating sensorimotor neuropathies, whereas moderately elevated levels have been reported in multiple sclerosis, inflammatory neuropathies, and motor neuron disease. Approximately 50% of patients with IgM monoclonal gammopathies and associated peripheral neuropathy have detectable MAG antibodies.

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Magnesium, RBC		Test Code: RCRP
CPT:	83735
Alternate Name:	RBC Magnesium
Methodology:	Calculation
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	5 mL whole blood processed to packed red blood cells.
Container:	Royal Blue top trace metal tube, lavender label
Special Instructions and/or Comments:
•Place whole blood in ice water immediately after collection. •Centrifuge tube within 15 minutes •Remove plasma and discard •Submit RBC’s remaining in bottom of tube •Refrigerate
Reference Range:
1.65-2.65 mmol/L
Clinical Utility:
Useful in the evaluation of magnesium nutritional status

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Magnesium, Serum		Test Code: MG
CPT:	83735
Methodology:	HNL Endpoint LPP Bichromatic endpoint
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
<15 days 1.2-2.2 mg/dL >15 days 1.8-2.4 mg/dL
Critical Values:
<1.0 mg/d >5.0 mg/dL
Clinical Utility:
Used in the evaluation of malabsorption and pancreatic disorders, renal clearance and to monitor patients receiving prolonged magnesium therapy.

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Magnesium, Urine Random		Test Code: RUMG
Includes:	83735 MethodologyEndpoint Testing ScheduleRoutine, daily Report Available1 day Minimum Volume5 mL random urine Container Plastic urine container Collection Random Special Instructions and/or CommentsTransport to the laboratory promptly. Reference Range<8 mg/dL Clinical Utility Used in the evaluation of magnesium loss, magnesium deficiency, magnesium balance and to monitor magnesium therapy.

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Magnesium, Urine , 24-Hour		Test Code: 24MG
Includes:	•Volume Measurement •Collection Period •Creatinine, Urine •Magnesium, Urine
CPT:	81050, 83735
Methodology:	Endpoint
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	Entire 24-Hour urine collection
Container:	Entire 24-Hour plastic urine container, no preservative
Collection:	24-Hour urine collection See special instructions for “24-Hour Urine Collection”, listed under Specimen Collection,Preparation, and Handling Section
Special Instructions and/or Comments:
Transport to the laboratory promptly.
Reference Range:
•Creatinine, 24-Hour Urine: 0.8-2.8 g/24 hours •Magnesium, 24-Hour Urine: 73-122 mg/24 hours
Clinical Utility:
Used in the evaluation of magnesium loss,magnesium deficiency, magnesium balance and to monitor magnesium therapy.

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Mammotone/Needle Biopsy, Breast
See Histopathology, Breast Biopsy

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Marijuana
See Cannabinoids, Blood
See Cannabinoids, Qualitative, Urine

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Mass CK-MB Fraction
See Creatine Phosphokinase Isoenzyme Profile

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Maternal Serum AFP
See Alpha-Fetoprotein, Maternal Serum

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MCKMB
See Creatine Phosphokinase Isoenzyme Profile

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Measles Antibody,
See Rubeola IgG Antibody, Immune Status

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Measles IgG Antibody OR
See Rubeola IgG Antibody, Immune Status

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Measles IgM, IFA		Test Code: MEIGM
CPT:	86765
Alternate Name:	• Measles IgM by IFA • Rubeola IgM Antibody
Methodology:	IFA
Testing Schedule:	Routine, 1 time per week
Report Available:	5-10 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top serum separator tube
Special Instructions and/or Comments:
• Centrifuge tube and transfer serum to plastic vial • Refrigerate
Reference Range:
<1:10 titer
Clinical Utility:
To aid in the determination of current or recent rubeola (measles) virus infection.

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Measles Titer
See Rubeola IgG Antibody, Immune Status

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Mebaral®
See Mephobarbital

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Mellaril®
See Thioridazine

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Meningococcal Antibody Profile, Vaccine Response		Test Code: MENAB
Includes:	IgG Antibodies to the following Neisseria meningitidis •Serogroups .........Serogroup A .........Serogroup C .........Serogroup Y .........Serogroup W-135
CPT:	86741 (x4)
Methodology:	Multi-Analyte Immuno Detection (MAID)
Testing Schedule:	Routine, 1 time per week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
• Please note if specimens are pre- or post vaccination. • Refrigerate
Reference Range:
Pre-Vaccination for Neisseria meningitidis Antibody •Serogroup A.................< 4.0 µg/mL •Serogroup C.................< 5.0 µg/mL •Serogroup Y.................< 4.0 µg/mL •Serogroup W-135........< 3.0 µg/mL
Clinical Utility:
•Neisseria meningitidis causes infectious diseases in both children and adults.Active immunization is performed with a polyvalent vaccine. •This profile measures IgG antibodies recognizing polysaccharide antigens from the four Neisseriameningitidis serogroups included in the licensed meningococcal vaccine. •The meningococcal vaccine response is best evaluated by testing both pre- and post- vaccination samples in parallel. A two-fold or greater increase for at least two serogroups is expected when comparing pre- and post-vaccination results. •Neisseria meningitidis IgG serogroup specificantibodies should develop approximately one month following immunization, and will decline markedly within two years.

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Mephobarbital		Test Code: MEPH
Includes:	•Mephobarbital •Phenobarbital metabolite
CPT:	80184, 82205
Alternate Name:	Mebaral®
Methodology:	Gas Chromatography (GC), Immunoassay (IA)
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	2 mL serum
Container:	Red top tube, no serumseparator
Reference Range:
Therapeutic •Mephobarbitial 0-5.0 .µg/Ml •Phenobarbital15-40 .µg/mL
Clinical Utility:
Useful for optimizing drug therapy, assessing toxicityand compliance monitoring.

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Meprobamate		Test Code: MEPR
CPT:	83805
Alternate Name:	Equagesic®; Equanil®; Miltown®
Methodology:	Gas Chromatogrphay (GC)
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Container:	Red top tube, no serum separator
Reference Range:
•Therapeutic 5-30 .µg/mL •Toxic >50 .µg/mL
Clinical Utility:
Useful for assessing toxicity or abuse.

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Mercury, Blood		Test Code: MRB
CPT:	83825
Methodology:	Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
Testing Schedule:	Routine, daily
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	2 mL EDTA whole blood
Container:	Royal Blue top trace metal tube, lavender label
Special Instructions and/or Comments:
•Store as whole blood in original tube. •DO NOT centrifuge, aliquot or freeze. •Refrigerate only.
Reference Range:
•Normal <10 ng/mL •Toxic >50 ng/mL
Clinical Utility:
Useful for, detecting Hg toxicity

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Mercury, 24-Hour Urine		Test Code: UMERC
Includes:	•Volume Measurement•Collection Period •Mercury, Urine
CPT:	81050, 83825
Methodology:	Inductively Coupled Plasma - Mass Spectrometry (ICP- MS)
Testing Schedule:	Routine, daily
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	20 mL aliquot of a well mixed 24-Hour urine collection
Container:	24-Hour plastic urine container, no preservative
Collection:	•Instruct the patient to void at the beginning of the collection period and discard the specimen. •Collect all urine including the final specimen voided at the end of the collection period. •Refrigerate during collection. •Container must be labeled with the patient’sname.
Special Instructions and/or Comments:
•Instruct patient not to void directly into container. •Transport to the laboratory promptly.
Reference Range:
•Normal<10 µg/specimen •Toxic concentration >50 µg/specimen
Clinical Utility:
Useful for, detecting Hg toxicity

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Mercury, Occupational Exposure, Random Urine		Test Code: RUMER
CPT:	83825
Methodology:	Inductively Coupled Plasma - Mass Spectrometry (ICP-MS), Enzymatic Colorimetric Assay
Testing Schedule:	Routine, Monday-Friday only
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	10 mL random urine
Container:	Plastic urine container, no metal cap or glued insert
Collection:	Abstain from seafood (especially shellfish) for 2 days prior to urine collection
Reference Range:
< 35 µg/g creatinine
Clinical Utility:
For screening potentially exposed workers for Hg toxicity in settings where a 24-hour collection is problematic

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Metanephrine, Fractionated, 24-Hour Urine		Test Code: FMET
Includes:	• Volume Measurement • Collection Period • Normetanephrine • Metanephrines, Total
CPT:	81050, 83835
Methodology:	Liquid Chromatography/Tandem MassSpectrometry (LC-MS/MS), Stable Isotope Dilution Analysis
Testing Schedule:	Routine, daily
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	25 mL aliquot of a well mixed 24-Hour urine collection
Container:	24-Hour plastic urine container Add 25 mL of 50% acetic acid at start of collection.
Collection:	•Tricyclic antidepressants, labetalol, and sotalol medications may elevate levels of metanephrines producing results which cannot be interpreted.If clinically feasible, it is optimal to discontinue these medications at least 1 week before collection. •Instruct the patient to void at the beginning of the collection period and discard the specimen. •Collect all urine including the final specimen voided at the end of the collection period. •Refrigerate during collection. •Container must be labeled with the patient’s name.
Special Instructions and/or Comments:
•Instruct patient not to void directly into container. •Transport to the laboratory promptly.
Reference Range:
See report.
Clinical Utility:
Useful for a first- and second-order screening test for the presumptive diagnosis of catecholamine-secreting pheochromocytomas and paragangliomas. Confirming positive plasma metanephrine results.

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Metanephrines, Fractionated, Free, Plasma		Test Code: PLMET
Includes:	Metanephrine, Free Normetanephrine, Free
CPT:	83835
Methodology:	Liquid Chromatography / Tandem MassSpectrometry (LC-MS/MS)
Testing Schedule:	Routine, daily
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	4 mL EDTA plasma
Container:	3 lavender top (EDTA) tubes
Special Instructions and/or Comments:
Centrifuge, transfer to plastic aliquot tube andfreeze.Once frozen, transport specimen submergedin dry ice.
Reference Range:
•Metanephrine, Free <0.50 nmol/L •Normetanephrine, Free<0.90 nmol/L
Clinical Utility:
Useful for, screening test for presumptive diagnosis of catecholamine-secreting pheochromocytomas or paragangliomas

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Methadone, Quantitative, Blood		Test Code: BMTHD
CPT:	83840
Methodology:	LC/MS/MS or GC/MS
Testing Schedule:	Once/week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mLs whole blood
Container:	Gray top or lavendar top tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Therapeutic range:.............75-1100 ng/mL.
Clinical Utility:
To detect use of methadone and toxicity.

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Methadone, Urine		Test Code: MTDN
CPT:	80101
Alternate Name:	Dolophine®
Methodology:	Immunoassay (IA)
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL urine
Container:	Plastic urine container
Special Instructions and/or Comments:
If for forensic or legal purposes, submit specimenwith a completed Drug Testing Request and Chain-of-Custody (HNL-53) Form or Blood AlcoholToxicology Request/Chain-of-Custody (LAB-53)Form.
Reference Range:
None detected (unless on methadone therapy).
Clinical Utility:
Useful for the detection and positive identificationfor methadone in urine.Confirmation by GC/MS (gas chromatography/mass spectrometry) available upon request.Contact Customer Care 610-402-8170 for instructions.

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Methadone, Urine, GCMS		Test Code: GCUM
Includes:	Identification andquantitation of methadone by GCMS
CPT:	83840
Methodology:	Gas Chromatography/Mass Spectroscopy(GC/MS)
Testing Schedule:	3 times/week
Report Available:	2-4 days
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Special Instructions and/or Comments:
If for forensic or legal purposes, submit specimen with a completed Drug Testing Request and Chain-of-Custody (HNL-53) Form or Blood Alcohol Toxicology Request/Chain-of-Custody (LAB-32)Form.
Reference Range:
None present
Clinical Utility:
Useful for the detection and positive identification of methadone in urine.

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Methamphetamine
See Amphetamines, Qualitative, Urine

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Methanol		Test Code: MEOH
Includes:	Identification and quantitation of methanol
CPT:	84600
Alternate Name:	Methyl Alcohol; Wood Alcohol
Methodology:	Gas Chromatography (GC)
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum, plasma, whole blood OR urine
Container:	Red top tube, gray top (sodium fluoride) tube OR plastic urine container
Special Instructions and/or Comments:
Note on Requisition Form if methanol ingested.
Reference Range:
•Normal none detected. •Potentially toxic >10 mg/dL
Clinical Utility:
Useful for detecting ingestion and toxicity.

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Methemoglobin		Test Code: METHB
CPT:	83050
Methodology:	Photometry
Testing Schedule:	Routine, STAT
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	3 mL whole blood in lithium heparinized syringeOR 3 mL whole blood in green top (lithium heparin) tube or lithium heparin capillary tube
Container:	Lithium heparin syring OR green top (lithiumheparin) tube or lithium heparin capillary tube
Collection:	•Fill tube completely. •Collect anaerobically. •DO NOT uncap tube. •Transport to laboratory immediately
Special Instructions and/or Comments:
Due to time sensitivity of test, sample collection must be performed at a draw site located within the hospital.
Reference Range:
<3%
Clinical Utility:
Used in the evaluation of methemoglobinemia and identifying cyanosis due to other causes.

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Methotrexate		Test Code: METX
CPT:	80299
Methodology:	Immunoassay (IA)
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Red top tube, no serum separator
Collection:	Collection is determined by dosing protocol.
Special Instructions and/or Comments:
Protect from light by wrapping the entire tube with aluminum foil.
Reference Range:
Therapeutic range dependant on dosage Potentially toxic •>5.0 umol/L 24 hours after high dose therapy •>0.5 umol/L 48 hours after high dose therapy
Clinical Utility:
Useful for following therapy to assess drug clearance and potential toxicity

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Methyl Alcohol
See Methanol

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Methylenetetrahydrofolate Reductase Mutation		Test Code: MTHR
Includes:	NOTE Best when used as a follow-up to previously elevated test results obtained in the Homocysteine assay.
CPT:	83891, 83892, 83896 X 5, 83903, 83908 X 2, 83912
Alternate Name:	MTHFR
Methodology:	Direct Mutation Analysis
Testing Schedule:	Routine, 1 time per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	5 mL whole blood
Container:	Yellow top (ACD Solution A) tube
Special Instructions and/or Comments:
•Forward to Laboratory promptly •Store as whole blood in original tube at room temperature. •DO NOT centrifuge, aliquot, refrigerate or freeze.
Reference Range:
Negative Mutation not detected.
Clinical Utility:
Useful For, direct mutation analysis for the MTHFR C677T mutation should be reserved for patients with CAD, acute MI, peripheral vascular artery disease, stroke, or venous thromboembolism who have increased basal homocysteine levels or an abnormal methionine load test. At this time, the utility of direct mutation analysis for the MTHFR C677T mutation in an asymptomatic family member with a normal basal homocysteine level is unknown.

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Methylmalonic Acid (MMA), Quantitative		Test Code: METHA
CPT:	83921
Alternate Name:	MMA
Methodology:	Liquid Chromatography/Tandem MassSpectrometry (LC-MS/MS), stable Isotope Dilution Analysis
Testing Schedule:	Routine, Monday-Friday only
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Centrifuge, transfer to plastic aliquot tube and freeze. Once frozen, transport specimen submerged in dry ice.
Reference Range:
< 0.40 umol/L
Clinical Utility:
Useful for, evaluating children with signs and symptoms of methylmalonic acidemia Screening for the differential diagnosis of signs and symptoms associated with a variety of causes of cobalamin deficiency. Serum MMA may be a more reliable marker of cobalamin deficiency than direct cobalamin determination.

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Mexilet®
See Mexiletine

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Mexiletine		Test Code: MEXL
CPT:	80299
Alternate Name:	Mexilet®
Methodology:	High Performance Liquid Chromatography (HPLC)
Testing Schedule:	3 times per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	3 mL serum
Container:	Red top tube, no serumseparator
Collection:	Collect just before administration of the next dose and after patient has been receiving the drug at least 3 days.
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Therapeutic concentration (trough value)....0.8-2.0 µg/mL
Critical Values:
Toxic concentration (trough value)...........> 2.00 µg/mL
Clinical Utility:
Useful for, assessing achievement of optimal therapeutic concentrations and assessing potential toxicity

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Microalbumin, 24-Hour Urine		Test Code: MALB
Includes:	•Volume Measurement •Collection Period •Microalbumin, Urine
CPT:	82043, 81050
Alternate Name:	24-Hour Microalbumin; Microalbuminuria
Methodology:	End Point
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL aliquot of a well-mixed 24-Hour urine collection
Special Instructions and/or Comments:
Transport to the laboratory promptly.
Reference Range:
<15 mcg/minute for an ambulatory nonexercising subject.
Clinical Utility:
Microalbuminuria is used as an indicator of increased risk to develop renal disease in diabetics and as a predictor of mortality due to cardiovascular disease.

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Microalbumin, Random Urine		Test Code: RMALB
CPT:	82043
Alternate Name:	Microalbuminuria; Random Urine Microalbumin
Methodology:	End Point
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Collection:	Freshly voided random urine
Special Instructions and/or Comments:
Refrigerate
Reference Range:
<2 mg/dL
Clinical Utility:
Microalbuminuria is used as an indicator of increased risk to develop renal disease in diabetics and as a predictor of mortality due to cardiovascular disease.

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Microalbumin/Creatinine Ratio, Random Urine		Test Code: RUMCR
Includes:	•Quantitative determination of •Microalbumin, Urine, Random •Creatinine, Urine, Random •Microalbumin/Creatinine Ratio
CPT:	82570, 82043
Alternate Name:	Micro/creat ratio
Methodology:	See individual test listings.
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Collection:	Freshly voided random urine
Special Instructions and/or Comments:
Refrigerate
Reference Range:
<20 mg albumin/g creatinine
Clinical Utility:
Microalbuminuria is used as an indicator of increased risk to develop renal disease in diabetics and as a predictor of mortality due to cardiovascular disease.

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Microalbuminuria
See Microalbumin, 24-Hour Urine
See Microalbumin, Random Urine
See Microalbumin/Creatinine Ratio,Random Urine

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Microbilirubin, Total
See Bilirubin, Total Neonatal (Infants <15 days old)

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Microhemagglutination Test for T. pallidum
See Treponemal Confirmation Assay, TP-PA

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Microhematocrit
See Hematocrit, Whole Blood

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Microscopic Examination, Urine
See Urinalysis with Reflex Microscopic

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Microscopic Section
See HistopathologyMicrosomal Autoantibody
See Thyroid Peroxidase Autoantibody

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Microsporidia Detection Stain		Test Code: MICSP
CPT:	87015, 87207
Alternate Name:	Microsporidia Identification
Methodology:	Trichrome Blue Stain
Testing Schedule:	Routine, Monday-Friday only
Report Available:	5-7 days Specimen Requirements
Specimen Requirements:
Minimum Volume:	10 g preserved stool
Container:	ParaPak® containing 10% Formalin OR ECOFIX preservative
Collection:	•Patient should avoid use of anti-diarrhea lmedication (ie, Pepto Dismol®) for 7-14 days prior to collection. •The presence of barium will interfere with thistest.
Reference Range:
Negative
Clinical Utility:
Useful for, diagnosis of intestinal microsporidiosis inpatients with AIDS and others with unexplained diarrhea, especially after overseas travel

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Microsporidia Identification
See Microsporidia Detection Stain

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Mielke Bleeding Time
See Bleeding Time, Template

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Miscellaneous Electrolytes
See Electrolytes, Body Fluid

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Mitochondrial Antibody
See Mitochondrial Autoantibody

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Mitochondrial Autoantibody		Test Code: AMA
Includes:	• Mitochondrial Autoantibody Reflexed when appropriate • Quantitative titer on positive screens
CPT:	86255,Reflexed when appropriate,86256
Alternate Name:	AMA; Anti-Mitochondrial Antibody; Mitochondrial Antibody
Methodology:	Indirect Fluorescent Antibody (IFA)
Testing Schedule:	Routine, 2 times per week
Report Available:	3-5 days (may be extended if further dilutions required)
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
Negative titer <1:20
Clinical Utility:
Anti-Mitochondrial antibodies (AMA) have been reported in greater than 90% of patients with PrimaryBiliary Cirrhosis (PBC). AMA are also occasionally found in patients with chronic active hepatitis,cryptogenic cirrhosis and in patients with clinical but nobiochemical evidence of liver disease.

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MMA
See Methylmalonic Acid (MMA),Quantitative

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Monocional Gammopathy Screening Profile		Test Code: MGSP
Includes:	• Serum Protein Electrophoresis (SPRE) • Serum Free Light Chain Profile (SFLCP) • Reflex Tests when necessary • Immunoglobulin G, A, M (IGG, IGA, IGM) • Serum Protein Immunofixation (IME)
CPT:	84155, 84165, 83883 (X2); Reflex: 82784 (X3), 86334
Alternate Name:	Myeloma Screening Profile
Methodology:	Electrophoresis Nephelometry
Testing Schedule:	See individual test listings
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	4 mL serum
Container:	2 Gold top, SST tubes
Reference Range:
See individual test listings
Clinical Utility:
Screening for monoclonal gammopathies.

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Mononucleosis Screen		Test Code: MON
CPT:	86308
Alternate Name:	Heterophile Agglutinin Test; Infectious Mononucleosis Screening Test; Monospot™ Test ;Mono Test
Methodology:	Latex Agglutination
Testing Schedule:	Routine; STAT testingavailable
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
Negative no antibodies detected NOTE When clinical suspicion is strong and the “Monotest” is negative, it is suggested that a reflex Epstein Barr Virus (EBV) antibody profile be requested.
Clinical Utility:
Screening test for Infectious Mononucleosis or EBV infection.

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Monospot™ Test
See Mononucleosis Screen

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Mono Test
See Mononucleosis Screen

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Morphine
See Opiates, Quantitative, Blood
See Opiates, Qualitative, Urine

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Morphine Total, Blood		Test Code: BTM
CPT:	83925
Methodology:	GC/MS
Testing Schedule:	Routine; once per week
Report Available:	1-2 weeks
Specimen Requirements:
Container:	2 mL whole blood Container Gray top (sodium fluoride) tube OR 1 lavender top(EDTA) tube
Special Instructions and/or Comments:
If for forensic purposes, submit with chain of custody
Reference Range:
Not available, dependent on dose and tolerance
Clinical Utility:
Useful for establishing toxicity and generally used forforensic testing.

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MPO
See Neutrophil Cytoplasmic Autoantibody Profile

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MRSA Screen		Test Code: MRSAS
CPT:	87641
Alternate Name:	Screen for Methicillin Resistant Staphylococcus aureus
Methodology:	Real-time polymerase chain reaction (PCR) assay (nucleic acid amplified probe)
Testing Schedule:	Routine; daily
Report Available:	1 day
Specimen Requirements:
Collection:	Culture swab of anterior nares using a red capped CultureSwab (liquid Stuart collection swab). 1. Place the culture swab in the first inch of the nose and gently rotate five times. DO NOT touch the shaft of the swab when collecting. 2. Insert the same swab into the other nostril and roll the swab five times. 3. Insert the swab back into the transport tube. 4. Label and send to the lab.
Reference Range:
Negative for MRSA
Critical Values:
Positive for MRSA
Clinical Utility:
Used to actively screen patients for MRSA colonization in order to reduce the risk of potential transmission.

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MsAFP
See Alpha-Fetoprotein, Maternal Serum

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MS Profile
See Multiple Sclerosis Screen

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MS Screen
See Multiple Sclerosis Screen

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MTHFR
See Methylene Tetrahydrofolate Reductase Mutation

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Mucin Clot Test		Test Code: MUCN
CPT:	83872
Alternate Name:	Fluid, Mucin; Ropes Test , Synovial Fluid; Synovial Fluid, Mucin Clot Test
Methodology:	Manual
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	2 mL synovial fluid
Container:	Sterile tube OR red top tube, no serum separator
Special Instructions and/or Comments:
Refrigerate
Reference Range:
A compact large clot surrounded by a clear solution = “GOOD” rating.
Clinical Utility:
Used as a qualitative assessment of the degree of polymerization of synovial fluid hyaluronate in inflammatory conditions.

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Multiple Sclerosis Screen		Test Code: MSSEV
Includes:	• IgG and Albumin Quantitations, CSF • IgG and Albumin Quantitations, Serum • Oligoclonal Banding, CSF and Serum • Protein Electrophoresis, CSF (CPEP) • Protein Electrophoresis, Serum (SPEP) • Calculated: IgG/Albumin CSF Ratio, Combined CSF/Serum Ratio, and IgG Synthesis Rate
CPT:	82040, 82042, 82784(X6), 83873, 83916
Alternate Name:	MS Profile; MS Screen
Methodology:	See individual test listings.
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mL serum AND 3 mL cerebrospinal fluid
Container:	Gold top (serum separator) tube AND sterile conical tube
Special Instructions and/or Comments:
• Testing cannot be performed unless both cerebrospinal fluid AND serum are submitted. • Serum and CSF should be drawn on the same day for most reliable results.
Reference Range:
Accompanies Report
Clinical Utility:
Used to support diagnosis of multiple sclerosis and to provide a monitor of treatment efficacy. Also useful in patients with silicone get implants who have M.S. like symptoms.

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Multiple Sclerosis Screen
See MSSEV

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Mumps Screen
See Mumps Virus IgG Antibody,Immune Status

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Mumps Titer
See Mumps Virus IgG Antibody,Immune Status

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Mumps Virus IgG Antibody Immune Status		Test Code: MUVA
CPT:	86735
Alternate Name:	Mumps Immune Status; Mumps Screen; Mumps Titer
Methodology:	Enzyme-Linked Immunosorbent Assay (ELISA)
Testing Schedule:	Routine, 2 times per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
See table. Mumps IgG Antibody Screen ELISA Antibody Index Interpretation Comment <0.91 Negative Indicates no detectable IgG antibody to Mumps virus. Patient is not immune and therefore susceptible to primary infection. If primary infection is suspected, specimen obtained within days after onset of symptoms may not contain detectable IgG antibodies, and second specimen should be obtained in 14-21 days. 0.91-1.09 Equivocal IgG antibody levels to Mumps virus may not equate with immunity. Suggest a new specimen be submitted for testing. >1.09 Positive Indicates presence of detectable IgG antibody to Mumps virus. Patient is immune. Results suggest past infection or immunization. Immunity to exogenous reinfection is lifelong, so second attacks of disease are virtually unknown
Clinical Utility:
The presence of mumps specific-IgG antibodies would suggest previous immunization or exposure to the mumps virus. In non-immunized individuals, when paired acute and convalescent specimens (two to three weeks apart) are evaluated with a 4-fold or greater rise in mumps specific-IgG antibodies, an acute infection is suggested and should be corroborated with clinical presentation.

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Mumps Virus IgM Antibody		Test Code: MUVM
Includes:	NOTE: DO NOT confuse with orders for Mumps Virus IgG Antibody, which is utilized for the evaluation of immune status.
CPT:	86735
Methodology:	Enzyme Immunoassay (EIA)
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Reference Range:
Ab Index Interpretation <0.80 Negative (IgM Antibody not detected) Critical Values Positive results are reported to the appropriate State Department of Health. Clinical Utility The presence of mumps specific-IgM antibodies would suggest an acute infection and should be corroborated with clinical presentation. Please note that results from a single IgM assay should not be used as the sole determinate of an acute infection, as IgM test results may yield false positive results and low levels of IgM antibody can persist for more than 12 months postinfection. If an acute infection is indicated,submit an additional specimen in two or more weeks for IgM and IgG testing.

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Muscle Biopsy
See Histopathology, Muscle Biopsy

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Myasthenia Gravis Profile		Test Code: MYGP
Includes:	•Acetylcholine Receptor Binding Autoantibody •Acetylcholine Receptor Blocking Autoantibody •Acetylcholine Receptor Modulating Autoantibody •Striated Muscle Autoantibody
CPT:	83519 x 3, 86256
Methodology:	Radioimmunoassay (RIA) Indirect Fluorescent antibody (IFA)
Testing Schedule:	Routine, 1 time per week
Report Available:	7-10 days
Specimen Requirements:
Minimum Volume:	3 mL serum
Container:	Gold top (serum separator) tube Special Instructions and/or CommentsRefrigerate
Reference Range:
See individual test listings.
Clinical Utility:
Myasthenia Gravis (MG), the most common neuromuscular transmission disorder, is an antibody-mediated autoimmune disease that stems from a loss of acetylcholine receptors (AChR) at neuromuscular junctions. AChR autoantibodies are diagnostic of MG, and are found in 85-90% of MG patients. More specifically: •AChR Binding Autoantibodies are present most frequently in MG and provide the most reliable information for diagnostic screening. •AChR Blocking Autoantibodies are directed against the neurotransmitter binding site and maybe the only AChR Autoantibody in about 1% of MG patients. •A small portion of patients with early on set or ocular-restricted MG may have only AChR Modulating Autoantibodies. •Striated Muscle Autoantibody is used to diagnose myopathic disorders, and is found in 80-100% of patients with MG and thymoma.

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Mycobacteria Culture
See Culture, Mycobacteria

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Mycobacterium Identification by DNA Probe
See Acid Fast Bacilli, DNA Probe

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Mycobacterium gordonae
See Acid Fast Bacilli, DNA Probe

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Mycobacterium Stain
See Acid-Fast Stain

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Mycophenolic Acid		Test Code: MYPH
CPT:	80299
Alternate Name:	Cellcept, Mycophenolic Acid Glucoronide, Mycophenolate, Mofetil.
Methodology:	Tandem Mass Spectrometry (MS/MS)
Testing Schedule:	Routine, daily
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Red top (no serum separator) tube
Reference Range:
Mycophenolic Acid...............1.0-3.5 ug/mL MPA Glucuronide..................35 - 100 ug/mL
Clinical Utility:
Useful for monitoring therapy with cellcept to ensure adequate blood levels and avoid over immunosuppression

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Mycoplasma Antibodies
See Mycoplasma pneumoniae Antibody Profile

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Mycoplasma by Complement Fixation
See Mycoplasma pneumoniae Antibody Profile

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Mycoplasma IgG/IgM
See Mycoplasma pneumoniae Antibody Profile

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Mycoplasma pneumoniae Antibody Profile		Test Code: MYCP
Includes:	Mycoplasma pneumoniae IgG and IgM antibodies for evaluation of current or recent infection
CPT:	86738 (x2)
Alternate Name:	Eaton Agent Titer; M. pneumoniae Titer;Mycoplasma Antibodies; Mycoplasma byComplement Fixation; Mycoplasma IgG/IgM;Mycoplasma pneumoniae Titer; PPLO Titer;Primary Atypical Pneumonia Titer
Methodology:	Enzyme-Linked Immunosorbent Assay (ELISA)
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Specimen Requirements:
Reference RangeSee table. Mycoplasma Profile Interpretation Chart IgG IgM Interpretation N N No serological evidence of recent or past Mycoplasma pneumoniae infection. Consideration of symptom onset with time of testing is important. A follow-up “convalescent” specimen may be warranted if results do not correlate with clinical presentation. N P Suggest very early “acute” primary infection. This pattern warrants a second specimen to document seroconversion. Repeat testing in 10-14 days is suggested. P P Suggests current or recent infection with Mycoplasma pneumoniae. Results should be interpreted in light of clinical presentation. P N Suggests past infection with Mycoplasma pneumoniae

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Mycoplasma T-Strain Culture, Genital
See Culture, Ureaplasma urealyticum

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Myelin Associated Glycoprotein Autoantibody
See MAG Antibody Profile

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Myelin Basic Protein, Cerebrospinal Fluid		Test Code: MBP
CPT:	83873
Methodology:	RIA
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	2 mL cerebrospinal fluid
Container:	Plastic vial
Special Instructions and/or Comments:
Centrifuge, transfer to plastic aliquot tube and freeze.Once frozen, transport specimen submergedin dry ice.
Reference Range:
< 4.1ng/mL
Clinical Utility:
Useful for detecting active demyelination in a variety of disorders involving the CNS.

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Myeloperoxidase Antibody
See Neutrophil Cytoplasmic Autoantibody Profile

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Myoglobin, Serum		Test Code: SMYOB
CPT:	83874
Methodology:	Microparticle Enzyme Immunoassay (MEIA)
Testing Schedule:	Daily, Mon.-Sat., Routine
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top tube (serum separator) tube
Special Instructions and/or Comments:
Centrifuge, transfer to plastic aliquot tube and freeze. Once frozen, transport specimen submergedin dry ice.
Reference Range:
< 116.3 ng/mL
Clinical Utility:
Useful for assessing muscle damage from any cause.

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Myoglobin, Qualitative, Urine		Test Code: MYOG
CPT:	83874
Methodology:	Manual
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Collection:	Freshly voided random urine
Reference Range:
Negative
Clinical Utility:
Used to detect myoglobin, a protein released from muscle after muscle damage.

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Mysoline®
See Primidone

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6-monoacetylmorphine, Urine, GCMS,		Test Code: GCU6
Includes:	Identification and quantitation of the heroin metabolite (6-monoacetylmorphine) by GCMS
CPT:	83925
Methodology:	Gas Chromatography/Mass Spectroscopy(GC/MS)
Testing Schedule:	3 times/week
Report Available:	2-4 days
Specimen Requirements:
Minimum Volume:	5 mL random urine
Special Instructions and/or Comments:
If for forensic or legal purposes, submit specimen with acompleted Drug Testing Request and Chain-of-Custody(HNL-53) Form or Blood Alcohol Toxicology Request/Chain-of-Custody (LAB-32) Form.
Reference Range:
None present
Clinical Utility:
Useful for the detection and positive identification of thespecific major heroin metabolite (6-monoacetylmo phine) in urine.

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MutationHemochromatosis PCR
See Hemochromatosis DNA Mutation