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B12
See Vitamin B12, Serum

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B27
See HLA-B27

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B2GP1 Antibodies G/A/M
See Beta-2-Glycoprotein-1Autoantibody Profile

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B. pertussis Ab
See Bordetella pertussis Antibody Profile

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Babesia
See Blood Parasites

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Babesia Antibodies
See Babesia microti Antibody Profile

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Babesia G/M
See Babesia microti Antibody Profile

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Babesia microti Antibody		Test Code: BABES
Includes:	IgG and IgM Antibodies
CPT:	86753 (x2)
Alternate Name:	Babesia Antibodies; Babesia G/M; Babesia Titer
Methodology:	Indirect Fluorescent Antibody (IFA)
Testing Schedule:	Routine, 2 times per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	Volume1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
<1:16 for both
Clinical Utility:
Useful for Babesia specific IgG (greater than or equal to 1:512) is concsistent with recent infection; antibody concentrations generally peak within one month of Exposure.

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Babesia titer
See Babesia microti Antibody Profile

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Baby Bilirubin
See Bilirubin, Total Neonatal (Infants <15 days old)

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Bacterial Antigen Profile		Test Code: BACG
Includes:	• Haemophilus influenzae Type b Antigen • Neisseria menigitidis Antigen groups A, C, Y, W135, B and E. coli K1 • Streptococcus pneumoniae Antigen • Group B/E coli K1 Ag Detection
CPT:	86403 (X5)
Alternate Name:	Bactigen™; Group B Strep Antigen, CSF; H. influenzae Type b Antigen, CSF; Neisseria meningitidis Antigen; Strep pneumoniae Antigen Methodology:Latex Agglutination Testing Schedule
Testing Schedule:	Routine, daily
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	1 mL cerebrospinal fluid
Container:	Sterile conical tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Negative
Clinical Utility:
Useful for an aid to diagnose bacterial meningitis

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Bacterial Culture, Aerobic
See Culture, Fluid, Aerobic
See Culture, Tissue, Aerobic
See Culture, Wound, Aerobic

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Bacterial Culture, Anaerobic
See Culture, Anaerobic/Aerobic

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Bacterial Identification
See Culture, Bacterial, Referred for Identification

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Bacterial Identification and Susceptibility
See Culture, Bacterial, Referred for Identification

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Bacterial Smear
See Gram Stain

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Bactigen™
See Bacterial Antigen Profile

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Barbiturate Screen, Blood
See Barbiturates, Quantitative, Serum

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Barbiturates, Quantitative, Serum or Blood		Test Code: SEHY
Includes:	• Identification and quantitation of: • Amobarbital • Butabarbital • Butalbital • Mephobarbital • Pentobarbital • Secobarbital
CPT:	80100
Alternate Name:	Barbiturate Screen, Blood
Methodology:	Gas Chromatography (GC)
Testing Schedule:	Routine, STAT testing available
Report Available:	Routine: 1 day; STAT: 2 hours
Reference Range:
Negative
Clinical Utility:
Useful for the specific identification and quantitation of barbiturates in serum.

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Barbiturates, Qualitative, Urine		Test Code: BBIT
Includes:	Screening for barbiturates, to include: • Amobarbital • Butabarbital • Butalbital • Pentobarbital • Phenobarbital • Secobarbital
CPT:	80101
Methodology:	Immunoassay (IA)
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Special Instructions and/or Comments:
If for forensic or legal purposes, submit specimen with a completed Drug Testing Request and Chain-of-Custody (HNL-53) Form or Blood Alcohol Toxicology Request/Chain-of-Custody (LAB-53) Form in plastic evidence bag.
Reference Range:
Negative
Clinical Utility:
Useful for qualitative screen useful for detection of drug abuse/use of barbiturates. Confirmation of a positive screening result by GC/MS is strongly recommended.

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Barbiturates, Urine, GCMS		Test Code: GCUB
Includes:	identification and quantitation by GCMS: •Amobarbital •Butalbital •Pentobarbital •Phenobarbital •Secobarbital
CPT:	82205
Methodology:	Gas Chromatography/Mass Spectroscopy (GC/MS)
Testing Schedule:	3 times/week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Special Instructions and/or Comments:
If for forensic or legal purposes, submit specimen with a completed Drug Testing Request and Chain-of-Custody (HNL-53) Form or Blood Alcohol Toxicology Request/Chain-of-Custody (LAB-32) Form.
Reference Range:
None present
Clinical Utility:
Useful for detection and positive identification of specific barbiturates in urine.

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Bartonella Antibody Profile		Test Code: CATSD
Includes:	IgG and IgM Antibodies to: Bartonella henselae Bartonella quintana
CPT:	86611 (x2), 86611 (x2)
Alternate Name:	Cat Scratch Disease Antibody Profile
Methodology:	Indirect Fluorescent Antibody (IFA)
Testing Schedule:	Routine, 2 times per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Centrifuge, transfer to plastic aliquot tube and freeze. Once frozen, transport specimen submerged in dry ice. eference Range: • IgG:..................<1:128 • IgM:.................<1:20
Clinical Utility:
Useful for rapid diagnosis of bartonella infections. Especially in the context of a cat scratch or Histopathology showing typical features of stellate microabscesses and/or positive Warthin-Starry stain.

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Basic Metabolic Panel		Test Code: BMP
Includes:	• Calcium • Carbon dioxide (CO2) • Chloride • Creatinine • Glucose • Potassium • Sodium • Urea nitrogen (BUN) • Anion Gap Calculation • Glomerular Filtration Rate Calculation (GFR)
CPT:	80048
Methodology:	See individual test listings
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
• GFR Calculation is not performed when: ..................1. Patient is <20 years of age. ..................2. A renal steady state is not present. ..................3. Sex of patient is unkown. African-American GFR: multiply reported GFR by 1.21
Reference Range:
See individual test listings.
Critical Values:
See individual test listings.
Clinical Utility:
Used to evaluate blood glucose; electrolyte, fluid and acid base balances and kidney function.

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BCAA
See CA 15-3

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BCR/ABL, Qualitative		Test Code: BCR/ABLQAL (CoPath ONLY)
Includes:	Discrimination of the fusion transcripts related to translocations associated with CML (b2a2; b3a2; e1a2)
Alternate Name:	BCR/ABL Translocation
Methodology:	Multiplex RT-PCR Performed on the Luminex 2000 Platform
Testing Schedule:	Routine, 1 time per week
Report Available:	5-10 days
Specimen Requirements:
Minimum Volume:	2 mL whole blood
Container:	Lavender top (EDTA) tube
Special Instructions and/or Comments:
• Store as whole blood in original tube at room temperature • DO NOT centrifuge, aliquot or freeze
Reference Range:
BCR/ABL translocation not detected.
Clinical Utility:
To aid in the pathological evaluation and diagnosis of leukemia. The detection of BCR/ABL in chronic myeloid leukemia (CML) patients is useful prognostically and therapeutically.

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Beef Tapeworm
See Parasite Identification

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Bence Jones Protein
See Protein Electrophoresis, Urine

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Bence Jones Protein, Quantitative
See Free Light Chains, Quantitative, 24- Hour Urine

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Benzodiazepines, Qualitative, Urine		Test Code: BNDZ
Includes:	Screening for benzodiazepines and metabolites, to include: • Alprazolam • Chlordiazepoxide • Diazepam • Flurazepam • Nordiazepam • Oxazepam • Temazepam
CPT:	80101
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Reference Range:
None detected
Clinical Utility:
A qualitative screen useful for detection of drug abuse/use of benzodiazepines. Confirmation of a positive screening result by GC/MS is strongly recommended.

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Benzodiazepines, Quant, Urine		Test Code: GCUZ
Includes:	Identification and quantitation of benzodiazepines to include: • alpha-hydroxyalprazolam • alpha-hydroxymidazolam • diazepam • hydroxyethylflurazepam • lorazepam • nordiazepam • oxazepam • temazepam
CPT:	80154
Methodology:	Liquid Chromatography - Tandem Mass Spectroscopy
Testing Schedule:	3 times/week
Report Available:	2-4 days
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Special Instructions and/or Comments:
If for forensic or legal purposes, submit specimen with a completed Drug Testing Request and Chain-of-Custody (HNL-53) Form or Blood Alcohol Toxicology Request/Chain-of-Custody (LAB-32) Form.
Reference Range:
None present
Clinical Utility:
Useful for the detection and positive identification of specific benzodiazepines in urine.

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Benzodiazepines, LC/MS		Test Code: BENZ
Includes:	Identification and quantitation of benzodiazepines : • alprazolam: • alpha-hydroxyalprazolam • clonazepam • 7-aminoclonazepam • chlordiazepoxide • diazepam • lorazepam • nordiazepam • oxazepam • temazepam
CPT:	80154
Methodology:	LC/MS/MS
Testing Schedule:	Once per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	2 mL whole blood, serum or plasma Minimum Volume: 1 mL
Container:	Gray top, red, top or lavendar top tube
Special Instructions and/or Comments:
Submit specimen with Chain-of-Custody if testing is for Forensic purposes.
Reference Range:
• alprazolam:..............................Therapeutic 10-100ng/mL • alpha-hydroxyalprazolam........Not established • clonazepam................Therapeutic 10-75ng/mL • chlordiazepoxide.......Therapeutic 400-2000 ng/mL • 7-aminoclonazepam...Concentrations following chronic therapy with 6 mg/day of clonazepan: 20-140 ng/mL • diazepam....................Therapeutic 100-1000ng/mL • lorazepam...................Therapeutic 100-1000ng/mL • nordiazepam...............Therapeutic 100-1000ng/mL • oxazepam....................Therapeutic 200-1400ng/mL • temazepam..................Peak concentrations 200-1100ng/mL
Clinical Utility:
Identification and quantitation of benzodiazepine use or abuse in whole blood, serum or plasma.

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Benzoylecgonine
See Cocaine, Qualitative, Urine

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Beta-2-Glycoprotein-1 Autoantibody Profile		Test Code: B2GP
Includes:	IgG, IgA and IgM Beta-2- Glycoprotein-1 Autoantibodies NOTE: Testing is best utilized when performed in parallel with a Cardiolipin Autoantibody Profile.
CPT:	86146 (x3)
Alternate Name:	B2GP1 Antibodies G/A/M; Anti-Beta-2-Glycoprotein-1 Antibody Profile
Methodology:	Enzyme-Linked Immunosorbent Assay (ELISA)
Testing Schedule:	Routine, 1 time per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
• Beta-2-Glycoprotein-1 IgG:.......................<20 U/mL • Beta-2-Glycoprotein-1 IgA:.......................<10 U/mL • Beta-2-Glycoprotein-1 IgM:..................... <10 U/mL
Clinical Utility:
Beta-2-GPI autoantibodies are found in patients with antiphospholipid syndrome (APS) and are associated with increased risk of venous and arterial thrombosis and thrombocytopenia. Beta2-GPI autoantibodies are found only in patients with autoimmune diseases, while cardiolipin autoantibodies can be transiently found in infectious diseases

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Beta2-Microglobulin, Serum		Test Code: BMIC
CPT:	82232
Methodology:	Microparticle Enzyme Immunoassay (MEIA)
Testing Schedule:	Routine, 1 time per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Reference Range:
0.7-3.4 mg/L
Clinical Utility:
Beta-2-Microglobulin is a low-molecular weight protein found on the cell surfaces of all nucleated cells and shed into the blood, particularly by tumor cells and lymphocytes. Due to its small size, it passes through the glomerular membrane, but normally less than 1% is excreted due to absorption in the proximal tubules of the kidney. Therefore, high plasma levels of BMB occur in renal failure, inflammation, and neoplasms, especially those associated with B-lymphocytes. It’s particularly useful in monitoring kidney transplant recipients.

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Beta2-Microglobulin, Urine		Test Code: UBMIC
Includes:	• PH • Beta Microglobulin, Urine
CPT:	82232
Methodology:	Nephelometry
Testing Schedule:	Routine, 1 time per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	5 mL urine
Container:	Plastic urine container
Collection:	Instruct patient to void, then drink full glass of water and provide urine sample within one hour. Transport to laboratory as soon as possible for Referral Testing personnel to adjust pH.
Special Instructions and/or Comments:
• Collect Mon.-Fri. ONLY before 1400 • No Holidays • Specimen MUST arrive in the laboratory before 1400 • Referral Testing will adjust ph of urine to between 6 & 8 usine NAOH • Refrigerate
Reference Range:
<0.03 mg/L
Clinical Utility:
Beta-2-microglobulin (B2M) is a low molecular-weight protein synthesized by all nuclueated cells. B2M is a clinically useful marker for following treatment response of patients with malignant lymphoma or multiple myeloma. B2M is also elevated in benign diseases; including rheumatoid arthritis, systemic lupuserythe matosus, sarcoidosis and some viral diseases.

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Beta2-Transferrin
See Beta2-Transferrin, Cerebrospinal Fluid Associated

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B2-Transferrin, FLD		Test Code: CAB2T
Includes:	Qualitative assessment for presence of CSF-associated Beta2-Transferrin in fluid suspected to be cerebrospinal fluid in nature.
CPT:	86335
Alternate Name:	Beta2-Transferrin; CSF- Associated Beta2-Transferrin; CSF B2T
Methodology:	Nepholometry
Testing Schedule:	Routine, daily
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	0.5 mL nose OR ear leakage fluid
Container:	Red top tube, no serum separator
Collection:	Obtain as much fluid as possible from nose or ear leakage, avoiding contamination during collection.
Reference Range:
Negative, no beta-2-transferrin (spinal fluid) detected.
Clinical Utility:
Useful fo the detection of spinal fluid in body fluids, such as ear or nasal fluid

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Beta-Hemolytic Strep Culture, Genital
See Culture, Genital, Group B, Beta- Hemolytic Strep Screen

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Beta-Hemolytic Strep Group B Screen
See Culture, Genital, Group B, Beta- Hemolytic Strep Screen

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Beta-Hemolytic Strep Group A Screen
See Culture, Throat, Group A Beta-Hemolytic Streptococci Only

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Beta-Hemolytic Strep Culture, Throat
See Culture, Throat, Group A Beta-Hemolytic Streptococci Only

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Beta-Hydroxybutyric Acid		Test Code: BHBA
CPT:	82010
Alternate Name:	BHB; b-Hydroxybutyrate
Methodology:	Spectrophotometric
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum OR plasma
Container:	Red top tube, Gold SST Tube OR gray top (sodium fluoride) tube
Special Instructions and/or Comments:
Centrifuge, transfer serum or plasma to plastic aliquot tube and refrigerate.
Reference Range:
• Children:......................0.02-0.29 mmol/L • Adults: .........................0.0-0.42 mmol/L
Clinical Utility:
Useful for Beta-hydroxybutryrate is the predominant ketone body and is useful for the detection andmonitoring of ketoacidosis.

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Beta Human Chorionic Gonadotropin, Serum		Test Code: BHCG
CPT:	84702
Alternate Name:	hCG, Beta Subunit; hCG, Quantitative; Human Chorionic Gonadotropin, Quantitative, Serum; Pregnancy Test; Quantitative Beta Subunit hCG
Methodology:	Direct Chemiluminescence
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	1 Gold top (serum separator) tube
Reference Range:
• <10 mIU/mL • Inconclusive: 5-10 mIU/mL (Inconclusive results do not rule out pregnancy. If clinically warranted, repeat testing in 48 hours.) • Gestational Age: • 0.2-1 week:..................5-50 mIU/mL • 1-2 weeks:...................50-500 mIU/mL • 2-3 weeks:...................100-5,000 mIU/mL • 3-4 weeks:...................500-10,000 mIU/mL • 4-5 weeks:...................1,000-50,000 mIU/mL • 5-6 weeks:...................10,000-100,000 mIU/mL • 6-8 weeks:...................15,000-200,000 mIU/mL • 2-3 months:.................10,000-100,000 mIU/mL NOTE: A spuriously elevated BHCG result may be obtained in the presence of heterophil antibodies. Before making a final diagnosis based on an elevated or repetitively inconclusive BHCG result, the following measures, among others, may be used in confirming results: • Perform a qualitative Beta hCG Urine test. The absence of urinary hCG may suggest a falsely elevated serum result. • Perform an additional BHCG, with the use of heterophilic antibody blocking mechanism (not FDA approved). This test must be requested by a physician as “Beta HCG with heterophilic antibody blocking mechanism” (test code BHCGH).
Clinical Utility:
Used in the detection and progress of pregnancy; also used in the evaluation of some germ cell tumors.

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Beta Human Chorionic Gonadotropin, Urine		Test Code: URHCG
CPT:	81025
Alternate Name:	hCG, Qualitative, Urine; hCG, Urine; Human Chorionic Gonadotropin, Urine; Pregnancy Test; Qualitative Beta Subunit hCG, Urine; Urine Pregnancy Test
Methodology:	Membrane Based Enzyme Immunoassay
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	2 mL random urine
Container:	Plastic urine container
Collection:	NOTE: The first morning urine generally contains the highest concentration of hormone.
Special Instructions and/or Comments:
Testing is contraindicated on bloody specimens.
Reference Range:
Negative NOTE: This assay can detect levels of BHCG as low as 20 mIU/mL. A negative test may result from a very early pregnancy with low levels of BHCG or a urine specimen which is too dilute. If pregnancy is still suspected, the test should be repeated on a fresh specimen in 2-4 days.
Clinical Utility:
Primarily used for the confirmation of pregnancy. Urine hCG tests usually suffice for diagnosis of normal pregnancy when it has progressed beyond the first week after the first missed period.

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Beta Lipoprotein
See LDL Cholesterol, Direct

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BHBâ-Hydroxybutyrate
See Beta-Hydroxybutyric Acid

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Bile Acids		Test Code: CHLY
CPT:	82239
Alternate Name:	Cholyglycine
Methodology:	Enzymatic
Testing Schedule:	Routine, 2 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Collection:	Overnight fast required (8 hours, minimum)
Special Instructions and/or Comments:
Centrifuge, transfer to plastic aliquot tube and refrigerate.
Reference Range:
0.0-10.0 umol/L
Clinical Utility:
Bile Acids arer formed in the liver, from Cholesterol, stored and concentrated in the gallbladder, and excreted into the intestines in response to food. Elevated concentrations often suggest impaired hepatic clearance due to liver disease. Patients with intestinal malabsorption and metabolic disorders such as Gilbert’s disease do not exhibit elevated Bile Acids concentrations.

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Bilirubin, Amniotic Fluid		Test Code: ABIL
Includes:	Delta OD 450 spectral analysis
CPT:	82143
Alternate Name:	Amniotic Fluid Analysis for Erythroblastosis Fetalis; Amniotic Fluid Bilirubin; Delta OD 450
Methodology:	Spectrophotometric
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL amniotic fluid
Container:	Brown glass or plastic container
Collection:	Amniocentesis performed by physician
Special Instructions and/or Comments:
• Transport to the laboratory immediately. • Requisition must include weeks of gestation information. • Protect from light by wrapping the entire container with aluminum foil.
Clinical Utility:
Useful for determining the presence of fetal erythroblastosis.

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Bilirubin, Body Fluid		Test Code: FTBI
CPT:	82247
Alternate Name:	Body Fluid TBIL
Methodology:	Endpoint
Testing Schedule:	Routine, STAT testing available
Report Available:	1day
Specimen Requirements:
Minimum Volume:	1 mL body fluid
Container:	Red top tube, no serum separator
Special Instructions and/or Comments:
Protect from light by wrapping the entire tube with aluminum foil.
Reference Range:
None established, must be interpreted with clinical findings.

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Bilirubin, Conjugated
See Bilirubin, Direct, (Infants 15 days to adults)
See Bilirubin, Direct Neonatal, (Infants <15days old)

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Bilirubin, Direct (Infants 15 days to adults)		Test Code: DBIL
CPT:	82248
Alternate Name:	Bilirubin, Conjugated; Delta; Direct Bilirubin
Methodology:	HNL..................Endpoint LPP...................Bichromatic endpoint
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	• Infant:..........................0.1 mL serum • Adult:..........................1.0 mL serum
Container:	Gold top (serum separator) tube OR yellow, green or red BD Microtainer™ tube
Collection:	Avoid hemolysis.
Special Instructions and/or Comments:
• Transport to the laboratory immediately. • Protect from light by wrapping the entire tube with aluminum foil. NOTE: To maintain consistency in Bilirubin methodology, an infant who has had a Bilirubin, Direct Neonatal ordered and becomes >14 days old, should continue to have a Bilirubin, Direct Neonatal ordered– DO NOT SWITCH TO THE BILIRUBIN, DIRECT.
Reference Range:
0.0-0.4 mg/dL
Clinical Utility:
Used in the evaluation of hepatic, biliary and hemolytic disorders.

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Bilirubin, Direct Neonatal (Infants <15 days old)		Test Code: NDBL
CPT:	82248
Alternate Name:	Bilirubin, Conjugated; Direct Bilirubin
Methodology:	HNL...............Endpoint LPP................Bichromatic endpoint
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	0.1 mL serum
Container:	Yellow, green OR red BD Microtainer™ tube
Collection:	• Collect by heelstick. • Avoid hemolysis.
Special Instructions and/or Comments:
• Transport to the laboratory immediately. • Protect from light by wrapping the entire tube with aluminum foil. NOTE: To maintain consistency in Bilirubin methodology, an infant who has had a Bilirubin, Direct Neonatal ordered and becomes >14 days old, should continue to have a Bilirubin, Direct Neonatal ordered– DO NOT SWITCH TO THE BILIRUBIN, DIRECT.
Reference Range:
0.0-1.5 mg/dL
Clinical Utility:
Used in the evaluation of hepatic, biliary and hemolytic disorders.

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Bilirubin, Total Neonatal (Infants <15 days old)		Test Code: NBIL
CPT:	82247
Alternate Name:	Baby Bilirubin; Microbilirubin, Total; Total Bilirubin, Neonatal
Methodology:	HNL....................... Endpoint LPP.........................Bichromatic endpoint
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	0.1 mL serum
Container:	Yellow, green OR red BD Microtainer™ tube
Collection:	• Collect by heelstick. • Avoid hemolysis.
Special Instructions and/or Comments:
• Transport to the laboratory immediately.• Protect from light by wrapping the entire tube with aluminum foil. NOTE: To maintain consistency in Bilirubin methodology, an infant who has had a Bilirubin, Total Neonatal ordered and becomes >14 days old, should continue to have a Bilirubin, Total Neonatal ordered– DO NOT SWITCH TO THE BILIRUBIN, TOTAL.
Reference Range:
• 0 days:..............................0.2-5.0 mg/dL • 1 day: ..............................0.2-9.0 mg/dL • >2 days: ...........................0.2-13.0 mg/dL • >7 days:............................0.2-1.3 mg/dL
Critical Values:
>15.0 mg/dL
Clinical Utility:
Used in the evaluation of hepatic, biliary and hemolytic disorders.

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Bilirubin, Total (Infants 15 days to adults)		Test Code: TBIL
CPT:	82247
Alternate Name:	Total Bilirubin
Methodology:	HNL:................Endpoint LPP:.................Bichromatic endpoint
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	• Infant: 0.1 mL serum • Adult: 1 mL serum
Container:	Gold top (serum separator) tube OR yellow, green or red BD Microtainer™ tube
Collection:	Avoid hemolysis.
Special Instructions and/or Comments:
• Transport to the laboratory immediately. • Protect from light by wrapping the entire tube with aluminum foil. NOTE: To maintain consistency in Bilirubin methodology, an infant who has had a Bilirubin, Total Neonatal ordered and becomes >14 days old, should continue to have a Bilirubin, Total Neonatal ordered– DO NOT SWITCH TO THE BILIRUBIN, TOTAL.
Reference Range:
0.2-1.3 mg/dL
Critical Values:
>15.0 mg/dL
Clinical Utility:
Used in the evaluation of hepatic, biliary and hemolytic disorders.

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Bilirubin, Urine		Test Code: URBI
CPT:	81002
Alternate Name:	Ictotest for Bilirubin
Methodology:	Manual
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	1 mL random urine
Container:	Plastic urine container
Special Instructions and/or Comments:
• Refrigerate • Protect from light by wrapping the entire container with aluminum foil.
Reference Range:
Negative
Clinical Utility:
Used as a screen for hepatic and biliary disorders and obstruction.

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Biopsy
See Histopathology

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Biopsy, Breast
See Histopathology, Breast Biopsy

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Biopsy, Culture
See Culture, Tissue, Aerobic

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Biopsy Culture, Aerobic
See Culture, Tissue, Aerobic

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Biopsy Specimen Culture, Quantitative
See Culture, Tissue, Quantitative

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BJP (Bence Jones Protein)
See Protein Electrophoresis, Urine

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BK Virus, PCR, Blood		Test Code: BKVBL
CPT:	87799
Methodology:	Polymerase Chain Reaction (PCR)
Testing Schedule:	Routine, daily
Report Available:	2-4 days
Specimen Requirements:
Minimum Volume:	1 mL EDTA whole blood
Container:	Lavender top (EDTA) tube
Special Instructions and/or Comments:
• Store as whole blood in original tube. • DO NOT centrifuge, aliquot, or freeze. • Refrigerate only.
Reference Range:
Not detected. If detected the result is quantitative
Clinical Utility:
Useful for assessment of active BK Virus infection.

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BK Virus, PCR, Urine		Test Code: BKVUR
CPT:	87799
Methodology:	Polymerase Chain Reaction (PCR)
Testing Schedule:	Routine, daily
Report Available:	2-4 days
Specimen Requirements:
Minimum Volume:	5-10 mL random urine
Container:	Plastic urine container
Special Instructions and/or Comments:
Refrigerate.
Reference Range:
Not detected. If detected the result is quantitative.
Clinical Utility:
Useful for assessment of active BK Virus infection.

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Bladder Washings Cytology
See Cytopathology, Fluid

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Bleeding Time
See Bleeding Time, Template

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Bleeding Time, Template		Test Code: TBT
CPT:	85002
Alternate Name:	Bleeding Time; Capillary Bleeding Time; Ivy Bleeding Time; Mielke Bleeding Time; Template Bleeding Time
Methodology:	Standardized Incision
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	Flowing blood from lancet incision.
Container:	Filter paper
Collection:	NOTE: This collection procedure is performed by laboratory designated personnel only. 1 mm deep (pediatric 0.5 mm) incision is made on the volar surface of the forearm using a lancet specified for TBT testing. Welling blood is removed at 30 second intervals using filter paper without disturbing the platelet plug. Constant venous pressure of 40 mmHg for adults and 20 mmHg for children (<12 years old) is applied throughout the procedure. Testing is discontinued after 15 minutes if bleeding does not cease.
Special Instructions and/or Comments:
Platelet count must be >100,000/cumm to perform test. Medication containing aspirin should be suspended at least 1 week prior to testing.
Reference Range:
Adults & Children:.........2-8 minutes
Critical Values:
>15 minutes
Clinical Utility:
Used as a screening for coagulation abnormality; in particular to assess capillary and platelet function.

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Blood Acetone
See Acetone, Semiquantitative

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Blood Ammonia
See Ammonia, Plasma

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Blood Culture
See Culture, Blood

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Blood Culture, Aerobic/Anaerobic
See Culture, Blood

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Blood Culture, AFB
See Culture, Blood, Mycobacteria

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Blood Culture, Bacterial
See Culture, Blood

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Blood Culture, Fungus
See Culture, Blood, Fungus

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Blood Culture, TB
See Culture, Blood, Mycobacteria

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Blood Culture, MAI
See Culture, Blood, Mycobacteria

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Blood Gas, Arterial		Test Code: ABG
Includes:	• % oxygen saturation (sO2) • pH • pCO2 • pO2 • Bicarbonate (HCO3), Standard • Base excess or deficit, standard • TCO2
CPT:	82805
Alternate Name:	ABG
Methodology:	Potentiometry
Testing Schedule:	STAT testing only
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	• Pediatric: 100 µL heparinized (lithium heparin) arterial whole blood • Adult: 3 mL heparinized (lithium heparin) arterial whole blood
Container:	Heparinized blood gas syringe OR heparinized glass capillary tubes NOTE: It is impossible to maintain anaerobic integrity of a specimen if evacuated glass tubes are used.
Special Instructions and/or Comments:
• Transport to the laboratory immediately. • Must be tested within 30 minutes of collection • Collection sites listed in order of preference are: radial, brachial, and femoral arteries.
Reference Range:
• pH:..............................7.35-7.45 • pCO2: < 24 months..........27-40 mm Hg < 24 months Male.................35-48 mmHg Female..............32-45 mm/Hg • pO2: .........................>70 mm Hg Birth......................8-24 mm/Hg 5-10 min...............33-75 mm/Hg 30 min..................31-85 mm/Hg > 1 Hr...................55-80 mm/Hg 1 day.....................54-95 mm/Hg > 1 day..................83-108 mm/Hg • HCO3: ........................22-28 mEq/L < 2 mos................17-2 mEq/L 2 mos-2 yr............16-2 mEq/L Adult....................21-28 mEq/L • TCO2: ........................22-28 mEq/L < 2 mos................13-22 mEq/L 2 mos-19 yr..........20-28 mEq/L Adult >19.............22-29 mEq/L >60 yrs..................22-28 mEq/L • sO2: < 2 month:............40-90% > 2 month:............95-998
Critical Values:
• pH: ......................<7.20 or >7.55 • pCO2:...................<20 mm Hg or >60 mm Hg • pO2: .....................<60 mm Hg • TCO2:...................<15 or >40 mEq/L
Clinical Utility:
Used to evaluate oxygenation, cardiorespiratory function and acid/base balance.

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Blood Gas, Arterial Cord Blood		Test Code: ABGCB
Includes:	• pH • pCO2 • Bicarbonate (HCO3), Standard • Base excess or deficit, standard
CPT:	82803
Alternate Name:	Cord Blood Gas
Methodology:	Potentiometry
Testing Schedule:	STAT testing only
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	3 mL heparinized (lithium heparin) arterial cord whole blood
Container:	Heparinized blood gas syringe
Special Instructions and/or Comments:
• Transport to the laboratory immediately. • Must be tested within 30 minutes of collection.
Reference Range:
• pH:..............................7.26-7.50 • pCO2: ........................33-65 mm Hg • HCO3:........................17-27 mEq/L
Clinical Utility:
Used to assess newborn respiratory status.

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Blood Gas, Arterial with Co-oximetry		Test Code: CABG
Includes:	• Arterial blood gas • Carboxyhemoglobin • Methemoglobin • Oxyhemoglobin • Total Hemoglobin, Calculated • O2 Content
CPT:	82805, 83050:, 82375
Methodology:	See individual test listings
Testing Schedule:	STAT testing only
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	3 mL heparinized (lithium heparin) arterial whole blood
Container:	Heparinized blood gas syringe
Special Instructions and/or Comments:
• Transport to the laboratory immediately. • Must be tested within 30 minutes of collection.
Reference Range:
• pH: ...............................7.35-7.45 • pCO2: < 24 months.........27-40 mm Hg < 24 months Male................35-48 mmHg Female............32-45 mm/Hg • pO2: ..........................>70 mm Hg Birth....................8-24 mm/Hg 5-10 min.............33-75 mm/Hg 30 min.................31-85 mm/Hg > 1 Hr..................55-80 mm/Hg 1 day...................54-95 mm/Hg > 1 day................83-108 mm/Hg • HCO3: .......................22-28 mEq/L Adult...................21-28 mEq/L • TCO2: .......................22-28 mEq/L < 2 mos...............13-22 mEq/L 2 mos-19 yr.........20-28 mEq/L Adult >19............22-29 mEq/L >60 yrs................22-28 mEq/L • sO2: < 2 month: .........40-90% • O2 Content: ...............15-33 mL/dL • Carboxyhemoglobin: •>2 pks/d.............8-9%
Critical Values:
• pH:...........................<7.20 or >7.55 • pCO2:.........................<20 or >60 mm Hg • pO2:............................<60 mm Hg • TCO2:.........................<15 or >40 mEq/L • Carboxyhemoglobin:..>20%
Clinical Utility:
Used to evaluate cardiorespiratory function, acid/base balance, inhalation injury and oxygen saturation.

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Blood Gas, Arterial/Venous Oxygen Saturation Difference		Test Code: AVO2P
Includes:	• Blood Gas, Arterial • Blood Gas, Venous • Oxygen saturation difference
CPT:	82805 (x2)
Alternate Name:	AVO2
Testing Schedule:	STAT testing only
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	3 mL heparinized (lithium heparin) arterial whole blood AND 3 mL heparinized venous whole blood
Container:	Heparinized blood gas syringe
Special Instructions and/or Comments:
• Transport to the laboratory immediately. • Must be tested within 30 minutes of collection.
Reference Range:
Content difference: 4.5-5.5 volume % O2 NOTE: The AVO2 Difference is the oxygen difference in volume percent between arterial and venous blood samples. • An increased AVO2 Difference: May reflect more complete extraction of oxygen from the blood as is characteristic in tissues receiving decreased blood flow (i.e., CHF, shock) • A decreased AVO2 Difference: may reflect less extraction of oxygen from the blood than normal (i.e.,sepsis, high cardiac output).
Clinical Utility:
Used to measure the oxygen difference between arterial and venous blood samples.

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Blood Gas, Venous		Test Code: VBG
Includes:	• pH • pCO2 • pO2 • % oxygen saturation (sO2) • Bicarbonate (HCO3), Standard • Base excess or deficit, standard
CPT:	82805
Alternate Name:	VBG; Venous Blood Gas
Methodology:	Potentiometry
Testing Schedule:	STAT testing only
Report Available:	1 day
Specimen Requirements:
Container:	3 mL heparinized (lithium heparin) venous cord blood Container:Heparinized blood gas syringe OR green top (lithium heparin) tube
Collection:	Collect specimen into air free heparinized syringe or green top (lithium heparin) tube NOTE: If a green top tube is used, the tube must be removed from the Vacutainer® holder prior to the needle being removed from the patient’s arm.
Special Instructions and/or Comments:
Transport to the laboratory immediately.
Reference Range:
• Venous pCO2: • 0-15 days:............10-25 mm Hg • >15 days:.............40-50 mm Hg • pH: .................................7.33-7.43 • pO2:...............................approximately 40 mm Hg • sO2:...............................approximately 75%
Clinical Utility:
Useful for evaluating cellular hypoxia and acid/base balance.

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Blood Gases, Venous Cord Blood		Test Code: VBGC
Includes:	• pH • pCO2 • Bicarbonate (HCO3), Standard • Base excess or deficit, standard
Alternate Name:	Cord Blood VBG
Methodology:	Potentiometry
Testing Schedule:	STAT testing only
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	3 mL heparinized (lithium heparin) venous cord blood
Container:	Heparinized blood gas syringe
Special Instructions and/or Comments:
Transport to the laboratory immediately.
Reference Range:
• pH: ....................7.22-7.46 • pCO2:.................32.8-48.6 mm Hg • HCO3:................18.9-23.9 mEq/L
Clinical Utility:
Used to evaluate cellular hypoxia and acid/base balance in the newborn.

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Blood Grouping and Rh Typing
See ABO and Rh (D) Type

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Blood Lactate
See Lactate, Plasma

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Blood NH3
See Ammonia, Plasma

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Blood NH4
See Ammonia, Plasma

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Blood, Occult, Stool
See Occult Blood, Stool

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Blood Parasites		Test Code: BPAR
Includes:	Examination of both thick and thin smears
CPT:	87207
Alternate Name:	Blood Smear for Trypanosomal/Filarial Parasites; Parasitology Examination for Malaria; Plasmodium Smear; Babesia
Methodology:	Giemsa Stain
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	6 slides (3 thick AND 3 thin)
Container:	Slides. NOTE: Blood may be collected using a lavender top vacutainer. Smears must be made within 30 minutes of collection. Smears made at time of collection are preferred.
Collection:	Collect blood from venipuncture NOTE: Recommended procedure is for specimen to be obtained when patient spikes a fever. Optimal yield results from examination of a daytime specimen (ie, noon) and a night-time specimen (ie, midnight). Timing of sampling relates to geographic place of exposure.
Special Instructions and/or Comments:
If patient has traveled to an endemic area, the date of travel, area traveled and parasite suspected should be specified on the Requisition Form.
Reference Range:
Negative. If positive, organism is identified.
Clinical Utility:
A number of parasites can be recovered from blood specimens. These parasites include Plasmodium, Babesia, Trypanosoma, Leishmania, Toxoplasma and microfilariae. Species identification is accomplished by the reading of permanent blood smears. Identification of a parasite aids in patient diagnosis and treatment.

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Blood Smear for Trypanosomal/Filarial Parasites
See Blood Parasites

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Blood Type
See ABO and Rh (D) Type Blood Type
See ABO and Rh (D) Type, Directed Donor

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Blood Urea Nitrogen
See Urea Nitrogen, Serum

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BNP, Congestive Heart Failure Test
See B-type Natriuretic Peptide, Whole Blood

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Body Cavity Fluid Cytology
See Cytopathology, Fluid

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Body Fluid Albumin
See Albumin, Body Fluid

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Body Fluid Amylase
See Amylase, Body Fluid

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Body Fluid BUN
See Urea Nitrogen, Body Fluid

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Body Fluid Cell Count
See Cell Count, Body Fluid

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Body Fluid Creatinine
See Creatinine, Body Fluid

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Body Fluid Culture
See Culture, Fluid, Aerobic

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Body Fluid Electrolytes
See Electrolytes, Body Fluid

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Body Fluid Glucose
See Glucose, Body Fluid

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Body Fluid K
See Potassium, Body Fluid

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Body Fluid LDH
See Lactate Dehydrogenase, Body Fluid

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Body Fluid pH
See pH, Body Fluid

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Body Fluid Potassium
See Potassium, Body Fluid

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Body Fluid Protein
See Protein, Total, Body Fluid

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Body Fluid Sodium
See Sodium, Body Fluid

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Body Fluid TBIL
See Bilirubin, Body Fluid

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Body Fluid Uric Acid
See Uric Acid, Body Fluid

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Bone Alkaline Phosphatase
See Alkaline Phosphatase, Bone Specific

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Bordetella Abs
See Bordetella pertussis Antibody Profile

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Bordetella titer
See Bordetella pertussis Antibody Profile

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Bordetella pertussis Antibody Profile		Test Code: BPABP
Includes:	PT IgG, and IgA, FHA IgG and IgA
CPT:	86615 (x4)
Alternate Name:	Bordetella Abs; Bordetella titer; B. pertussis Ab; Pertussis Antibody Profile
Methodology:	Multi-Analyte Immunodetection (MAID) Testing Schedule: Routine, Mon. - Fri.
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	2 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
• PT IgG........................<40 units/mL • PT IgA.......................<5 units/mL • FHA IgG....................<84 units/mL • FHA IgA...................<39 units/mL
Clinical Utility:
Levels of antibodies recognizing pertussis toxin (PT) and filamentous hemagglutinin antigen (FHA) are typically increased following either vaccination or natural exposure to Bordetella pertussis. Increased levels of FHA IgG alone may represent crossreactive antibodies induced by infection with other Bordetella species, Mycoplasma pneumoniae, Chlamlydia pneumoniae or nonencapsulated Haemophilus influenzae.

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Bordetella, PCR		Test Code: BPPCR
Includes:	B.pertussis and B. parapertussis
CPT:	87801, 83907
Alternate Name:	Bordetella Pertussis/ Parapertussis, Pertussis,PCR, Whooping Cough
Methodology:	Realtime PCR
Testing Schedule:	Routine, daily
Report Available:	1-3 days
Specimen Requirements:
Collection:	Nasopharyngeal nylon flocked swab placed in universal transport media (UTM), refrigerate OR Nasopharyngeal Aspirate (not throat), frozen.
Special Instructions and/or Comments:
DO NOT use calcium- alginate swabs
Reference Range:
Not detected
Clinical Utility:
Bordetella DNA detection by PCR has a greater than 2-fold higher specificity than culture and can detect the presence of bacterial nucleic acid from non—viable pathogens compromised by either transit or antibiotic therapy.

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Borrelia burgdorferi Antibodies
See Lyme Disease Antibody Profile

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Borrelia burgdorferi C6 Peptide Antibody
See Lyme C6 Peptide Antibody

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Borrelia burgdorferi PCR, Blood
See Lyme, PCR, Blood

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Borrelia burgdorferi PCR, CSF
See Lyme, PCR, Cerebrospinal Fluid

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Borrelia burgdorferi Western Blot
See Lyme Disease Antibody,Western Blot

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Brain type Natriuretic Peptide
See B-type Natriuretic Peptide,Whole Blood

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Breast Aspiration Cytology
See Cytopathology, Needle Aspiration

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Breast Cancer Antigen
See CA 15-3

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Bromide, Blood		Test Code: BROM
CPT:	84311
Methodology:	Colorimetry
Testing Schedule:	Routine, daily
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	4 mL EDTA whole blood
Container:	Lavender top (EDTA) tube
Special Instructions and/or Comments:
• Store as whole blood in original tube. • DO NOT centrifuge, aliquot, or freeze. • Refrigerate only.
Reference Range:
• Therapeutic:.................1,000-2,000 µg/mL • Toxic:...........................> 3,000 µg/mL
Clinical Utility:
Useful for support of the serodiagnosis of brucellosis.

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Bronchial Brushing Smears
See Cytopathology, Direct Smears

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Bronchial Brush Rinse Cytology
See Cytopathology, Fluid

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Bronchial Washing Cytology
See Cytopathology, Fluid

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Bronchoscopy, Culture, Bacterial
See Culture, Bronchoscopy

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Bronchoscopy, Culture, Bacterial
See Culture, Bronchoscopy

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Brucella abortus Antibody Profile		Test Code: BRUAB
Includes:	IgG, and IgM Antibodies
CPT:	86622 x 3
Alternate Name:	Brucella Antibody; Brucella Titer
Methodology:	ELISA
Testing Schedule:	Routine, 3 times per week
Report Available:	5-7 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Gold top (serum separator) tube
Special Instructions and/or Comments:
Refrigerate
Reference Range:
Brucella IgG & IgM:........< .80U
Clinical Utility:
Useful for support of the serodiagnosis of brucellosis.

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Brucella Antibody
See Brucella abortus Antibody Profile

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Brucella Titer
See Brucella abortus Antibody Profile

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B-type Natriuretic Peptide, Whole Blood		Test Code: BNPT
CPT:	83880
Alternate Name:	BNP, Congestive Heart Failure Test; Brain type Natriuretic Peptide
Methodology:	Direct Chemiluminescence
Testing Schedule:	Routine, STAT testing available
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	2 mL whole blood
Container:	Lavender top (EDTA) tube
Special Instructions and/or Comments:
• Refrigerate uncentrifuged tube. • Must be tested within 24 hours of collection. • If delay in transport, centrifuge, transfer plasma plastic aliquot tube and freeze. Once frozen, transport specimen submerged in dry ice.
Reference Range:
<100 pg/mL
Clinical Utility:
Used in the evaluation of congestive heart failure.

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Bullous Pemphigoid Antibodies
See Histopathology, Skin Biopsy, Immunofluorescence

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BUN
See Urea Nitrogen, Serum

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Buprenorphine		Test Code: BUPN
Includes:	Screen for buprenorphine and norbuprenorphine, cutoff concentration 5ng/ml
CPT:	80101
Alternate Name:	Suboxone, Subutex
Methodology:	Immunoassay (IA)
Testing Schedule:	Routine, daily
Report Available:	1 day
Specimen Requirements:
Minimum Volume:	5 mL random urine
Container:	Plastic urine container
Special Instructions and/or Comments:
• This is a qualitative screen and result is reported as positive or negative. • Confirmation of a positive screening result by GC/MS or LC/MS is available upon request by calliong the Toxicology Lab at (610) 402-5850 • Chain of Custody optional
Reference Range:
Negative, unless taking buprenorphine
Clinical Utility:
Detect the ingestion and/or use of buprenorphine for monitoring compliance or drug abuse

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Buproprion		Test Code: BUPRP
Includes:	• Buproprion • Hydroxybuproprion
CPT:	82491
Alternate Name:	Wellbutrin
Methodology:	High Performance Liquid Chromatography (HPLC)
Testing Schedule:	Routine, 3 times per week
Report Available:	3-5 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Red top tube, no serum separator
Special Instructions and/or Comments:
• Refrigerate • Centrifuge tube and transfers serum to plastic vial
Reference Range:
Suggested Therapeutic range: • Buproprion:.....................50-100 ng/mL • Hydroxybuproprion:........600-2000 ng/mL

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Burn Culture
See Culture, Burn Wound

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Burn Culture, Quantitative
See Culture, Tissue, Quantitative

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Butalbital		Test Code: BUTAL
CPT:	82205
Alternate Name:	Fioricet; Fiorinal
Methodology:	Gas Chromatography
Testing Schedule:	Routine, 2 times a week; STAT testing available
Report Available:	1-3 days
Specimen Requirements:
Minimum Volume:	1 mL serum
Container:	Red top tube, no serum separator
Reference Range:
• Therpeutic:...................1-10 µg/mL • Toxic: ..........................7-40 µg/mL
Clinical Utility:
Useful for the identification and quantitation of butalbital in serum to asses toxicity or monitoring therapeutic range or possible abuse.