Case Histories
Blastoid Mantle Cell Lymphoma, Pleomorphic Type
Shereen M. F. Gheith, MD, PhD
Chief, Section of Molecular Pathology
Department of Pathology & Laboratory Medicine
Presenting Case
● An 83-year-old gentleman who presented for:
– progressive shortness of breath
● His cardiologist ordered a CBC:
– WBC of 17.5 THOU/CMM
– hemoglobin and hematocrit of 8.7g/dL and 24.5%
– platelet count of 28 THOU/CMM
● Past Medical History:
– bladder cancer 40 years prior, status post XRT and BCG treatment
– history of melanoma 30 years prior
– a kidney mass of unknown etiology since the year 2000
– History of hypertension, hyperlipidemia, and hypothyroidism; coronary artery disease status post stents  |
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 CT scan of the chest, abdomen, and pelvis showed retroperitoneal and mesenteric lymphadenopathy, bilateral inguinal lymphadenopathy and small mediastinal lymph nodes. |
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 Diagnosis: A perfect example of an uncommon entity: blastoid mantle cell lymphoma, pleomorphic type |
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