Case Histories

Blastoid Mantle Cell Lymphoma, Pleomorphic Type
Shereen M. F. Gheith, MD, PhD
Chief, Section of Molecular Pathology
Department of Pathology & Laboratory Medicine

 

Presenting Case
● An 83-year-old gentleman who presented for:
 – progressive shortness of breath
● His cardiologist ordered a CBC:
 – WBC of 17.5 THOU/CMM
 – hemoglobin and hematocrit of 8.7g/dL and 24.5%
 – platelet count of 28 THOU/CMM
● Past Medical History:
 – bladder cancer 40 years prior, status post XRT and BCG treatment
 – history of melanoma 30 years prior
 – a kidney mass of unknown etiology since the year 2000
 – History of hypertension, hyperlipidemia, and hypothyroidism; coronary artery disease status post stents
   
   

CT scan of the chest, abdomen, and pelvis showed retroperitoneal and mesenteric
lymphadenopathy, bilateral inguinal lymphadenopathy and small mediastinal lymph nodes.
 

Diagnosis:
A perfect example of an uncommon entity: blastoid mantle cell lymphoma, pleomorphic type

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